Risk assessment and management in cancer genetics /

The need to expand expertise in cancer genetics beyond highly specialized genetics clinics is increasingly being recognized. In response, this practical book provides oncologists, specialist nurses, genetic counsellors, family doctors, and geneticists with comprehensive and easy-to-use guidelines on risk assessment and appropriate management. The book focuses on common familial cancers such as breast, colorectal, ovary, prostate and melanoma, and separate chapters cover cancer predisposing syndromes such as neurofibromatosis, familial adenomatous polyposis and their management.Includes bibliographical references and index.How to evaluate a family history / Bronwyn Kerr -- Guidelines for referral in Europe / Fred H. Menko -- Guidelines for genetic counselling, testing, and referral in North America / Susan Domchek and Barbara L. Weber -- Principles and applications of gene testing for common cancers / D. Gareth R. Evans, Pål Møller and Bronwyn Kerr -- Risk estimation in breast cancer / D. Gareth R. Evans, Bronwyn Kerr and Fiona Lalloo -- Risk estimation in colorectal cancer / Fiona Lalloo -- Risk estimation in ovarian cancer / D. Gareth R. Evans -- Management of familial breast and breast-ovarian cancer in Europe / Pål Møller -- Management of familial breast and ovarian cancer in North America / Barbara C. McGillivray -- Management of familial adenomatous polyposis and other inherited polyposis syndromes / E. Sheridan and R. S. Houlston -- The management of hereditary non-polyposis colorectal cancer / H. F. A. Vasen, J. Burn, E. Sheridan, R. S. Houlston and F. Douglas -- Management and risk assessment of less common familial cancers / Sameer Jhavar and Rosalind Eeles -- The neurofibromatoses / J. M. Friedman -- Von Hippel-Lindau disease / Eamonn R. Maher -- Multiple endocrine neoplasias / Fiona Lalloo -- Gorlin syndrome / D. Gareth R. Evans -- Li-Fraumeni syndrome / J. M. Birch -- Other tumour predisposing syndromes / Fiona Lalloo and D. Gareth R. Evans -- The ethical and insurance issues of cancer genetics / Patrick J. Morrison.The need to expand expertise in cancer genetics beyond highly specialized genetics clinics is increasingly being recognized. In response, this practical book provides oncologists, specialist nurses, genetic counsellors, family doctors, and geneticists with comprehensive and easy-to-use guidelines on risk assessment and appropriate management. The book focuses on common familial cancers such as breast, colorectal, ovary, prostate and melanoma, and separate chapters cover cancer predisposing syndromes such as neurofibromatosis, familial adenomatous polyposis and their management