Nanosensoren für die biotechnologische und medizinische Forschung: Nanosensors for biotechnological and medical research

Nanosensors are introduced that enable a reliable and continuous monitoring of pH. The pH-nanosensors are obtained by covalent immobilisation of indicator dyes to different types of polymer particles. Additional reference dyes allow for a ratiometric and quantitative detection of signal changes. Possible applications are in biological and medical analytics, e. g. monitoring the cellular pH of cancer cells to evaluate drug effects, and also in micro-reactors and sensor-arrays