Add to ORKGIt is generally accepted that most T cell receptor (TcR) delta/gamma cells are CD4-CD8-. After in vitro culture; however, a low percentage of these cells express the CD8-alpha subunit. We show here that addition of recombinant interleukin (IL) 4 to IL 2-cultured murine TcR V-gamma-5 thymocytes induces the expression of CD8-alpha; CD8-beta is not expressed. Co-addition of the anti-IL 4 mAb 11B11 abrogates the induction of CD8-alpha expression, ruling out the possibility of a contaminant. Furthermore, we demonstrate that a substantial part of freshly prepared TcR V-gamma-5 thymocytes express CD8-alpha.It is generally accepted that most T cell receptor (TcR) delta/gamma cells are CD4-CD8-. After in vitro culture; however, a low percentage of t...
T cells expressing T cell receptor (TCR) complexes that lack CD3 delta, either due to deletion of th...
B2A2-CD4-8- cells represent a rare subpopulation of thymocytes normally comprising 0.5% of the total...
A simple culture system devoid of antigen-presenting cells was used to examine the ability of immobi...
It is generally accepted that most T cell receptor (TcR) delta/gamma cells are CD4-CD8-. After in vi...
CD4 and CD8 antigens are simultaneously expressed on most of the cortical thymocytes, that weakly ex...
Whereas most T cells express surface CD4 or CD8 molecules, a minority lacks both. CD4-8- cells usual...
The CD8 co-receptor can modulate CD8(+) T cell function through its contributions to T cell receptor...
Amongst CD4-CD8- (double negative) thymocytes there is a sizeable population (variable from strain t...
For the last two decades, available results have suggested that CD4 and CD8 are functional analogs w...
(B) CFSE dilution profiles of TCRγδCD25 pTα thymocytes cultured on an OP9-DL1 monolayer for 4 d with...
CD4 and CD8 T cells express αβ T cell receptors (TCR) and respectively function as helpers and cy...
With the hope of understanding how interleukin (IL)-4 and IL-13 modulated quality of anti-viral CD8(...
The cytokine production profile, focusing on interleukin-4 (IL-4), interferon-gamma (IFN-gamma) and ...
Human CD34(+) hematopoietic precursor cells cultured on delta-like ligand 1 expressing OP9 (OP9-DL1)...
In normal human subjects a small proportion of peripheral blood T-cells simultaneously express both ...
T cells expressing T cell receptor (TCR) complexes that lack CD3 delta, either due to deletion of th...
B2A2-CD4-8- cells represent a rare subpopulation of thymocytes normally comprising 0.5% of the total...
A simple culture system devoid of antigen-presenting cells was used to examine the ability of immobi...
It is generally accepted that most T cell receptor (TcR) delta/gamma cells are CD4-CD8-. After in vi...
CD4 and CD8 antigens are simultaneously expressed on most of the cortical thymocytes, that weakly ex...
Whereas most T cells express surface CD4 or CD8 molecules, a minority lacks both. CD4-8- cells usual...
The CD8 co-receptor can modulate CD8(+) T cell function through its contributions to T cell receptor...
Amongst CD4-CD8- (double negative) thymocytes there is a sizeable population (variable from strain t...
For the last two decades, available results have suggested that CD4 and CD8 are functional analogs w...
(B) CFSE dilution profiles of TCRγδCD25 pTα thymocytes cultured on an OP9-DL1 monolayer for 4 d with...
CD4 and CD8 T cells express αβ T cell receptors (TCR) and respectively function as helpers and cy...
With the hope of understanding how interleukin (IL)-4 and IL-13 modulated quality of anti-viral CD8(...
The cytokine production profile, focusing on interleukin-4 (IL-4), interferon-gamma (IFN-gamma) and ...
Human CD34(+) hematopoietic precursor cells cultured on delta-like ligand 1 expressing OP9 (OP9-DL1)...
In normal human subjects a small proportion of peripheral blood T-cells simultaneously express both ...
T cells expressing T cell receptor (TCR) complexes that lack CD3 delta, either due to deletion of th...
B2A2-CD4-8- cells represent a rare subpopulation of thymocytes normally comprising 0.5% of the total...
A simple culture system devoid of antigen-presenting cells was used to examine the ability of immobi...