: Aging represents the major risk factor for the onset and/or progression of various disorders including neurodegenerative diseases, metabolic disorders, and bone-related defects. As the average age of the population is predicted to exponentially increase in the coming years, understanding the molecular mechanisms underlying the development of aging-related diseases and the discovery of new therapeutic approaches remain pivotal. Well-reported hallmarks of aging are cellular senescence, genome instability, autophagy impairment, mitochondria dysfunction, dysbiosis, telomere attrition, metabolic dysregulation, epigenetic alterations, low-grade chronic inflammation, stem cell exhaustion, altered cell-to-cell communication and impaired proteosta...
Cellular senescence is an important protective mechanism against cell proliferation and has critical...
RNA-binding proteins are involved in every stage of the RNA life cycle and have a major impact on ce...
In the present study, we perform an association analysis focusing on the expression changes of 1344 ...
The expression of senescence-associated genes, which governs the progression and the maintenance of ...
Aging, an inevitable path of life defined by gradual deterioration of function and ultimately death....
Cellular senescence, a hallmark of aging, is defined as irreversible cell cycle arrest in response t...
With the aging of the global population, accumulating interest is focused on manipulating the fundam...
Senescence is the change in the biology of an organism as it ages. It can be caused by different fac...
This is the final version. Available on open access from Wiley via the DOI in this recordThe human g...
miRNAs are the most abundant RNA species to be found in cell-free blood, encapsulated within microv...
A globally ageing population means an increase in age-associated diseases with many facing a lower...
Diverse cell types in the central nervous system (CNS) are generated by a relatively small pool of n...
Abstract Cellular senescence serves as a powerful tumor suppressing mechanism that inhibits the prol...
Aging research is currently focusing on circulating functional markers that can help discriminate th...
Cellular senescence is an important protective mechanism against cell proliferation and has critical...
Cellular senescence is an important protective mechanism against cell proliferation and has critical...
RNA-binding proteins are involved in every stage of the RNA life cycle and have a major impact on ce...
In the present study, we perform an association analysis focusing on the expression changes of 1344 ...
The expression of senescence-associated genes, which governs the progression and the maintenance of ...
Aging, an inevitable path of life defined by gradual deterioration of function and ultimately death....
Cellular senescence, a hallmark of aging, is defined as irreversible cell cycle arrest in response t...
With the aging of the global population, accumulating interest is focused on manipulating the fundam...
Senescence is the change in the biology of an organism as it ages. It can be caused by different fac...
This is the final version. Available on open access from Wiley via the DOI in this recordThe human g...
miRNAs are the most abundant RNA species to be found in cell-free blood, encapsulated within microv...
A globally ageing population means an increase in age-associated diseases with many facing a lower...
Diverse cell types in the central nervous system (CNS) are generated by a relatively small pool of n...
Abstract Cellular senescence serves as a powerful tumor suppressing mechanism that inhibits the prol...
Aging research is currently focusing on circulating functional markers that can help discriminate th...
Cellular senescence is an important protective mechanism against cell proliferation and has critical...
Cellular senescence is an important protective mechanism against cell proliferation and has critical...
RNA-binding proteins are involved in every stage of the RNA life cycle and have a major impact on ce...
In the present study, we perform an association analysis focusing on the expression changes of 1344 ...