In hereditary eye diseases of the Retinitis pigmentosa (RP) type, rod photoreceptors degenerate in a mutation-dependent fashion, followed by mutation independent cone cell death. Until today, no adequate treatment is available, but efforts are made to gain more knowledge about the mechanism of photoreceptor degeneration. To do so various animal models are available, showing mutations and symptoms comparable to human patients. In this study three models for RP (rd1 mouse, S334ter rat, and P23H rat) and a cone degeneration model, the cpfl1 mouse were investigated, asking whether a CRE-mediated transcription repressor, the inducible cAMP early repressor (ICER) was expressed. Since ICER is known to be involved in cell death in many neuronal and...
The first steps in vision occur in the retina when rod and cone photoreceptors transform light into ...
The first steps in vision occur in the retina when rod and cone photoreceptors transform light into ...
The first steps in vision occur in the retina when rod and cone photoreceptors transform light into ...
In hereditary eye diseases of the Retinitis pigmentosa (RP) type, rod photoreceptors degenerate in a...
Retinitis pigmentosa (RP) groups a family of hereditary neurodegenerative diseases of the retina cha...
Retinitis pigmentosa (RP) groups a family of hereditary neurodegenerative diseases of the retina cha...
Purpose Retinal pigmentosa (RP) is a heterogeneous group of retinal degeneration with a multitude o...
Retinal degenerations are a major cause of blindness in human patients. The identification of endoge...
Retinal degenerations are a major cause of blindness in human patients. The identification of endoge...
Retinal degenerations are a major cause of blindness in human patients. The identification of endoge...
Retinitis pigmentosa (RP) denotes a group of genetically heterogeneous retinal degenerative disorder...
Retinitis pigmentosa (RP) denotes a group of genetically heterogeneous retinal degenerative disorder...
Netzhauterkrankungen, wie Retinitis pigmentosa, sind in der Bevölkerung weit verbreitet (1,5 Million...
Retinitis pigmentosa (RP) is an inherited disorder and the leading cause of visual impairment in the...
Mouse models of retinal degeneration are useful tools to study therapeutic approaches for patients a...
The first steps in vision occur in the retina when rod and cone photoreceptors transform light into ...
The first steps in vision occur in the retina when rod and cone photoreceptors transform light into ...
The first steps in vision occur in the retina when rod and cone photoreceptors transform light into ...
In hereditary eye diseases of the Retinitis pigmentosa (RP) type, rod photoreceptors degenerate in a...
Retinitis pigmentosa (RP) groups a family of hereditary neurodegenerative diseases of the retina cha...
Retinitis pigmentosa (RP) groups a family of hereditary neurodegenerative diseases of the retina cha...
Purpose Retinal pigmentosa (RP) is a heterogeneous group of retinal degeneration with a multitude o...
Retinal degenerations are a major cause of blindness in human patients. The identification of endoge...
Retinal degenerations are a major cause of blindness in human patients. The identification of endoge...
Retinal degenerations are a major cause of blindness in human patients. The identification of endoge...
Retinitis pigmentosa (RP) denotes a group of genetically heterogeneous retinal degenerative disorder...
Retinitis pigmentosa (RP) denotes a group of genetically heterogeneous retinal degenerative disorder...
Netzhauterkrankungen, wie Retinitis pigmentosa, sind in der Bevölkerung weit verbreitet (1,5 Million...
Retinitis pigmentosa (RP) is an inherited disorder and the leading cause of visual impairment in the...
Mouse models of retinal degeneration are useful tools to study therapeutic approaches for patients a...
The first steps in vision occur in the retina when rod and cone photoreceptors transform light into ...
The first steps in vision occur in the retina when rod and cone photoreceptors transform light into ...
The first steps in vision occur in the retina when rod and cone photoreceptors transform light into ...