The restriction fragment length polymorphism (RFLP) haplotypes of cystic fibrosis (CF) alleles vary between populations. To determine the distribution of two RFLPs (XV-2C and KM-19) that are tightly linked to the CF locus, we analyzed a white sample from five different states of Brazil. The haplotypes of 314 CF- and 237 non-CFbearing chromosomes were uniformly distributed over the five states. The XV-2C allele and haplotype frequencies and the degree of linkage disequilibrium were determined. These were similar to values previously reported in southern European countries but different from results reported for northern and central Europe and North America. In contrast, although KM-19 allele frequencies differed between Brazilian states and ...
The analysis of 2 diallelic loci (M470V and T854T) and a microsatellite IVS8(T)n of the cystic fibro...
The nature and frequency of cystic fibrosis mutations in Brazil is not uniform due to the highly var...
We analyzed 192 cystic fibrosis (CF) alleles in three Latin American countries: Mexico, Colombia, an...
The restriction fragment length polymorphism (RFLP) haplotypes of cystic fibrosis (CF) alleles vary ...
We have used PCR amplification of DNA obtained from Guthrie cards to identify the DF508 mutation and...
We have used PCR amplification of DNA obtained from Guthrie cards to identify the DF508 mutation and...
The frequencies of the ΔF508 deletion, the most common cystic fibrosis mutation in Europeans and Eur...
Cystic fibrosis (CF) is an autosomal recessive disease caused by at least 750 different mutations in...
To contribute to a better understanding of the origin and distribution of CFTR mutations in the Braz...
AbstractCystic Fibrosis (CF) is one of the most common single-gene defects in European descent popul...
In view of the reported variations of cystic fibrosis (CF) associated haplotypes among populations, ...
Cystic fibrosis (CF) is the most common autosomal recessive disease in the European (Caucasian) popu...
In view of the reported variations of cystic fibrosis (CF) associated haplotypes among populations, ...
Cystic fibrosis (CF) is the most common autosomal recessive disease of the Caucasian population. Amo...
Cystic fibrosis (CF) is the most common autosomal recessive disease in the European (Caucasian) popu...
The analysis of 2 diallelic loci (M470V and T854T) and a microsatellite IVS8(T)n of the cystic fibro...
The nature and frequency of cystic fibrosis mutations in Brazil is not uniform due to the highly var...
We analyzed 192 cystic fibrosis (CF) alleles in three Latin American countries: Mexico, Colombia, an...
The restriction fragment length polymorphism (RFLP) haplotypes of cystic fibrosis (CF) alleles vary ...
We have used PCR amplification of DNA obtained from Guthrie cards to identify the DF508 mutation and...
We have used PCR amplification of DNA obtained from Guthrie cards to identify the DF508 mutation and...
The frequencies of the ΔF508 deletion, the most common cystic fibrosis mutation in Europeans and Eur...
Cystic fibrosis (CF) is an autosomal recessive disease caused by at least 750 different mutations in...
To contribute to a better understanding of the origin and distribution of CFTR mutations in the Braz...
AbstractCystic Fibrosis (CF) is one of the most common single-gene defects in European descent popul...
In view of the reported variations of cystic fibrosis (CF) associated haplotypes among populations, ...
Cystic fibrosis (CF) is the most common autosomal recessive disease in the European (Caucasian) popu...
In view of the reported variations of cystic fibrosis (CF) associated haplotypes among populations, ...
Cystic fibrosis (CF) is the most common autosomal recessive disease of the Caucasian population. Amo...
Cystic fibrosis (CF) is the most common autosomal recessive disease in the European (Caucasian) popu...
The analysis of 2 diallelic loci (M470V and T854T) and a microsatellite IVS8(T)n of the cystic fibro...
The nature and frequency of cystic fibrosis mutations in Brazil is not uniform due to the highly var...
We analyzed 192 cystic fibrosis (CF) alleles in three Latin American countries: Mexico, Colombia, an...