Introduction: Poorly differentiated neuroendocrine carcinomas (NECs) are characterized by aggressive clinical course and poor prognosis. No reliable prognostic markers have been validated to date; thus, the definition of a specific NEC prognostic algorithm represents a clinical need. This study aimed to analyze a large NEC case series to validate the specific prognostic factors identified in previous studies on gastro-entero-pancreatic (GEP) and lung NECs and to assess if further prognostic parameters can be isolated. Methods: A pooled analysis of four NEC retrospective studies was performed to evaluate: the prognostic role of Ki-67 cut-off, the OS according to primary cancer site, and further prognostic parameters using multivariable Cox p...
Background: Gastric neuroendocrine neoplasms (NENs) are very heterogeneous, ranging from mostly indo...
IF 6.029International audienceBackgroundDiagnosis and management of poorly differentiated gastro-ent...
Neuroendocrine tumors of the rectum were regarded as benign, when Oberndorfer originally described t...
Introduction: Poorly differentiated neuroendocrine carcinomas (NECs) are characterized by aggressive...
Mixed adenoneuroendocrine carcinomas (MANECs) are composed of a poorly differentiated neuroendocrine...
Da Man,1,* Jingjing Wu,2,3,* Zhan Shen,1 Xiaoyi Zhu1 1Department of Colorectal Surgery, Shulan (Hang...
Background: High-grade neuroendocrine tumours and carcinomas (NET/NECs) behave aggressively, typical...
Pancreatic neuroendocrine tumours (pNETs) represent rare neoplasms of all NETs often presenting with...
Background/Aims: Gastroenteropancreatic (GEP) neuroendocrine carcinomas (NECs) are defined as neuroe...
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a complex family of tumors of widely ...
Background: High-grade neuroendocrine carcinoma (NEC) is a rare and aggressive variant of bladder ca...
Objectives: There is a pressing need to develop clinical management pathways for grade 3 (G3) gastro...
No validated prognostic tool is available for predicting overall survival (OS) of patients with well...
Background: Gastric neuroendocrine neoplasms (NENs) are very heterogeneous, ranging from mostly indo...
IF 6.029International audienceBackgroundDiagnosis and management of poorly differentiated gastro-ent...
Neuroendocrine tumors of the rectum were regarded as benign, when Oberndorfer originally described t...
Introduction: Poorly differentiated neuroendocrine carcinomas (NECs) are characterized by aggressive...
Mixed adenoneuroendocrine carcinomas (MANECs) are composed of a poorly differentiated neuroendocrine...
Da Man,1,* Jingjing Wu,2,3,* Zhan Shen,1 Xiaoyi Zhu1 1Department of Colorectal Surgery, Shulan (Hang...
Background: High-grade neuroendocrine tumours and carcinomas (NET/NECs) behave aggressively, typical...
Pancreatic neuroendocrine tumours (pNETs) represent rare neoplasms of all NETs often presenting with...
Background/Aims: Gastroenteropancreatic (GEP) neuroendocrine carcinomas (NECs) are defined as neuroe...
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a complex family of tumors of widely ...
Background: High-grade neuroendocrine carcinoma (NEC) is a rare and aggressive variant of bladder ca...
Objectives: There is a pressing need to develop clinical management pathways for grade 3 (G3) gastro...
No validated prognostic tool is available for predicting overall survival (OS) of patients with well...
Background: Gastric neuroendocrine neoplasms (NENs) are very heterogeneous, ranging from mostly indo...
IF 6.029International audienceBackgroundDiagnosis and management of poorly differentiated gastro-ent...
Neuroendocrine tumors of the rectum were regarded as benign, when Oberndorfer originally described t...