Chronic venous insufficiency (CVI) is a leading vascular disease whose clinical manifestations include varicose veins, edemas, venous ulcers, and venous hypertension, among others. Therapies targeting this medical issue are scarce, and so far, no single venous valve prosthesis is clinically available. Herein, we have designed a bi-leaflet transcatheter venous valve that consists of (i) elastin-like recombinamers, (ii) a textile mesh reinforcement, and (iii) a bioabsorbable magnesium stent structure. Mechanical characterization of the resulting biohybrid elastin-like venous valves (EVV) showed an anisotropic behavior equivalent to the native bovine saphenous vein valves and mechanical strength suitable for vascular implantation. The EVV also...
Venous disease will affect 1-3% of the western world at some point in their lives, yet there are few...
AbstractObjectiveThe aim of the study was to evaluate the use of a decellularised scaffold and its r...
Chronic venous insufficiency (CVI) is a medical disease caused as a result of incompetent vein valve...
Chronic venous insufficiency (CVI) is a leading vascular disease whose clinical manifestations inclu...
Chronic venous insufficiency (CVI) is a leading vascular disease whose clinical manifestations inclu...
Background: Chronic venous insufficiency (CVI) represents a major global health problem with increas...
Native venous valves enable proper return of blood to the heart. Under pathological conditions (e.g....
Valvular heart disease remains to be a major cause of death worldwide with increasing prevalence, mo...
Introduction: Chronic insufficiency of lower extremity venous valves represents a frequent structura...
Venous valve failure allows for the retrograde, or backward, flow of blood into the lower extremitie...
Venous ulcers of the lower limbs are one clinical manifestation of chronic venous insufficiency. Cur...
ObjectiveThe purpose of this study was to evaluate whether tissue-engineered human allogeneic vein v...
The mechanical properties of tissue-engineered heart valves still need to be improved to enable thei...
AbstractObjective: to develop a graft bearing an immunologically tolerated tissue-engineered venous ...
Chronic Venous Insufficiency (CVI) is a condition in present in almost 27% of adults in which an ins...
Venous disease will affect 1-3% of the western world at some point in their lives, yet there are few...
AbstractObjectiveThe aim of the study was to evaluate the use of a decellularised scaffold and its r...
Chronic venous insufficiency (CVI) is a medical disease caused as a result of incompetent vein valve...
Chronic venous insufficiency (CVI) is a leading vascular disease whose clinical manifestations inclu...
Chronic venous insufficiency (CVI) is a leading vascular disease whose clinical manifestations inclu...
Background: Chronic venous insufficiency (CVI) represents a major global health problem with increas...
Native venous valves enable proper return of blood to the heart. Under pathological conditions (e.g....
Valvular heart disease remains to be a major cause of death worldwide with increasing prevalence, mo...
Introduction: Chronic insufficiency of lower extremity venous valves represents a frequent structura...
Venous valve failure allows for the retrograde, or backward, flow of blood into the lower extremitie...
Venous ulcers of the lower limbs are one clinical manifestation of chronic venous insufficiency. Cur...
ObjectiveThe purpose of this study was to evaluate whether tissue-engineered human allogeneic vein v...
The mechanical properties of tissue-engineered heart valves still need to be improved to enable thei...
AbstractObjective: to develop a graft bearing an immunologically tolerated tissue-engineered venous ...
Chronic Venous Insufficiency (CVI) is a condition in present in almost 27% of adults in which an ins...
Venous disease will affect 1-3% of the western world at some point in their lives, yet there are few...
AbstractObjectiveThe aim of the study was to evaluate the use of a decellularised scaffold and its r...
Chronic venous insufficiency (CVI) is a medical disease caused as a result of incompetent vein valve...