Following a spinal cord injury (SCI), an inflammatory immune reaction is triggered which results in advanced secondary tissue damage. The systemic post-SCI immune response is poorly understood. This study aimed to extensively analyse the circulating immune cell composition in traumatic SCI patients in relation to clinical parameters. High-dimensional flow cytometry was performed on peripheral blood mononuclear cells of 18 traumatic SCI patients and 18 healthy controls to determine immune cell subsets. SCI blood samples were collected at multiple time points in the (sub)acute (0 days to 3 weeks post-SCI, (s)aSCI) and chronic (6 to >18 weeks post-SCI, cSCI) disease phase. Total and CD4+ T cell frequencies were increased in cSCI patients. B...
Detection of immune cells in the injured central nervous system (CNS) using morphological or histolo...
Die Entzündungsantwort nach einer traumatischen Rückenmarksschädigung (SCI) kann das neurologische R...
The study reviews findings of the recent experiments designed to investigate cytokine profile after ...
Following a spinal cord injury (SCI), an inflammatory immune reaction is triggered which results in ...
Traumatic spinal cord injury (SCI) induces changes in the immune system, both acutely and chronicall...
Infections are prevalent after spinal cord injury (SCI), constitute the main cause of death and are ...
Individuals with spinal cord injuries (SCI) exhibit increased susceptibility to infection, with pneu...
The inability to effectively control microbial infection is a leading cause of morbidity and mortali...
Background. Despite considerable interest in the search for a spinal cord injury (SCI) therapy, ther...
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with signific...
Traumatic spinal cord injury (SCI) results in motor, autonomic and sensory impairment, and is a cond...
Spinal cord injury (SCI) initiates detrimental cellular and molecular events that lead to acute and ...
Traumatic spinal cord injury (SCI) commonly results from falls, sport activities or traffic accident...
Individuals with spinal cord injury (SCI) have higher infection rates compared to those without SCI....
Pro- and anti-inflammatory cytokines might have a large impact on the secondary phase and on the neu...
Detection of immune cells in the injured central nervous system (CNS) using morphological or histolo...
Die Entzündungsantwort nach einer traumatischen Rückenmarksschädigung (SCI) kann das neurologische R...
The study reviews findings of the recent experiments designed to investigate cytokine profile after ...
Following a spinal cord injury (SCI), an inflammatory immune reaction is triggered which results in ...
Traumatic spinal cord injury (SCI) induces changes in the immune system, both acutely and chronicall...
Infections are prevalent after spinal cord injury (SCI), constitute the main cause of death and are ...
Individuals with spinal cord injuries (SCI) exhibit increased susceptibility to infection, with pneu...
The inability to effectively control microbial infection is a leading cause of morbidity and mortali...
Background. Despite considerable interest in the search for a spinal cord injury (SCI) therapy, ther...
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with signific...
Traumatic spinal cord injury (SCI) results in motor, autonomic and sensory impairment, and is a cond...
Spinal cord injury (SCI) initiates detrimental cellular and molecular events that lead to acute and ...
Traumatic spinal cord injury (SCI) commonly results from falls, sport activities or traffic accident...
Individuals with spinal cord injury (SCI) have higher infection rates compared to those without SCI....
Pro- and anti-inflammatory cytokines might have a large impact on the secondary phase and on the neu...
Detection of immune cells in the injured central nervous system (CNS) using morphological or histolo...
Die Entzündungsantwort nach einer traumatischen Rückenmarksschädigung (SCI) kann das neurologische R...
The study reviews findings of the recent experiments designed to investigate cytokine profile after ...