Retrieval studies have indicated that debonding of the stem cement interface in total hip arthroplasty precedes clinical failure of femoral components. This study addressed the mechanisms that play a role in the debonding process by analyzing how debonding is likely to proceed in the course of time. It was investigated whether debonding is an immediate process or if it is likely to develop slowly with time, which interface stress components contribute particularly to its progression, and whether the mechanical integrity of the cement mantle is likely to be compromised by the debonding process. To answer these questions, a 3-dimensional finite element model of a femoral total hip arthroplasty reconstruction was developed and used to simulate...