The 2018 European Food Safety Authority/European Chemicals Agency Guidance on the Identification of Endocrine Disruptors lacks clarity on how the presence or absence of substance-induced maternal thyroid hormone imbalance, or the potential for subsequent deleterious consequences in child neurodevelopment, should be established by toxicological assessments. To address these uncertainties, this narrative review evaluates human evidence on how altered maternal thyroid function may be associated with child neurodevelopmental outcomes; and seeks to identify parameters in human studies that appear most relevant for toxicological assessments. Serum levels of free thyroxine (fT4) and thyroid stimulating hormone (TSH) are most frequently measured wh...
This review covers recent findings on the main categories of thyroid hormone-disrupting chemicals an...
BACKGROUND: Several European countries, including Belgium, still suffer from mild iodine deficiency....
The aim of this review is to indicate the current position on the role of thyroxine (T4) and fetal b...
The 2018 European Food Safety Authority/European Chemicals Agency Guidance on the Identification of ...
13 pages, 1 figure, 5 tables.-- Special article: Clinical perspective.Several recent publications ha...
Maternal thyroid function during pregnancy is implicated in the neurodevelopment of the offspring, y...
Low maternal free thyroxine (FT4) has been associated with poor child neurodevelopment in some singl...
Introduction: Brain development is highly dependent on hormonal regulation. Exposure to chemicals di...
Background: Exposure to organochlorine compounds (OCs) can alter thyroid function in humans, and hyp...
Background: Several European countries, including Belgium, still suffer from mild iodine deficiency....
Iodine is necessary for thyroid hormones synthesis which in turn are essential for brain development...
Context: Low maternal free T4 (FT4) has been associated with poor child neurodevelopment in some sin...
Background: Thyroid hormone is essential for optimal fetal brain development. Evidence suggests that...
We present a comprehensive overview of changes in thyroxine (T4) and thyroid stimulating hormone (TS...
Context: Thyroid hormones are essential for neurodevelopment from early pregnancy onward. Yet popula...
This review covers recent findings on the main categories of thyroid hormone-disrupting chemicals an...
BACKGROUND: Several European countries, including Belgium, still suffer from mild iodine deficiency....
The aim of this review is to indicate the current position on the role of thyroxine (T4) and fetal b...
The 2018 European Food Safety Authority/European Chemicals Agency Guidance on the Identification of ...
13 pages, 1 figure, 5 tables.-- Special article: Clinical perspective.Several recent publications ha...
Maternal thyroid function during pregnancy is implicated in the neurodevelopment of the offspring, y...
Low maternal free thyroxine (FT4) has been associated with poor child neurodevelopment in some singl...
Introduction: Brain development is highly dependent on hormonal regulation. Exposure to chemicals di...
Background: Exposure to organochlorine compounds (OCs) can alter thyroid function in humans, and hyp...
Background: Several European countries, including Belgium, still suffer from mild iodine deficiency....
Iodine is necessary for thyroid hormones synthesis which in turn are essential for brain development...
Context: Low maternal free T4 (FT4) has been associated with poor child neurodevelopment in some sin...
Background: Thyroid hormone is essential for optimal fetal brain development. Evidence suggests that...
We present a comprehensive overview of changes in thyroxine (T4) and thyroid stimulating hormone (TS...
Context: Thyroid hormones are essential for neurodevelopment from early pregnancy onward. Yet popula...
This review covers recent findings on the main categories of thyroid hormone-disrupting chemicals an...
BACKGROUND: Several European countries, including Belgium, still suffer from mild iodine deficiency....
The aim of this review is to indicate the current position on the role of thyroxine (T4) and fetal b...