PurposeIncreased blood-brain barrier (BBB) permeability has been shown to play a significant role in the pathophysiology of cerebrovascular disease and it may provide an early functional marker of progression or treatment effects. The aim of the study was to investigate the test-retest reproducibility and influencing factors of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) in measuring subtle leakage in patients with cerebrovascular disease.Material and MethodsDCE-MRI (3T) was performed on two separate days in 16 patients (age 669 years) with cerebrovascular disease, prospectively. The leakage rate was quantified for white matter (WM) and gray matter (GM) using the Patlak graphical approach with individual vascular input ...
Background Main aim was assessment of regional blood–brain barrier (BBB) function by dynamic contras...
Cerebral small vessel disease (cSVD) comprises pathological processes of the small vessels in the br...
Heye, Anna K Thrippleton, Michael J Armitage, Paul A Valdes Hernandez, Maria Del C Makin, Stephen D ...
PurposeIncreased blood-brain barrier (BBB) permeability has been shown to play a significant role in...
Purpose: Dynamic contrast-enhanced (DCE) MRI can be used to measure blood-brain barrier (BBB) leakag...
Purpose: Dynamic contrast-enhanced (DCE) MRI can be used to measure blood-brain barrier (BBB) leakag...
Purpose: Dynamic contrast-enhanced (DCE) MRI can be used to measure blood-brain barrier (BBB) leakag...
Cerebral small vessel disease (SVD) is a common cause of strokes and dementia. The pathogenesis of ...
Objective: As blood-brain barrier (BBB) dysfunction may occur in normal aging but may also play a pi...
PURPOSE: Cerebral small vessel disease (cSVD) involves several pathologies affecting the small vesse...
BACKGROUND AND PURPOSE: Dynamic contrast-enhanced MRI (DCE-MRI) can be employed to assess the blood-...
PURPOSE: Dynamic contrast-enhanced (DCE) -MRI with Patlak model analysis is increasingly used to qua...
Blood–brain barrier (BBB) leakage can be measured using dynamic contrast‐enhanced magnetic resonance...
There is evidence that subtle breakdown of the blood–brain barrier (BBB) is a pathophysiological com...
Cerebral small vessel disease (cSVD) comprises pathological processes of the small vessels in the br...
Background Main aim was assessment of regional blood–brain barrier (BBB) function by dynamic contras...
Cerebral small vessel disease (cSVD) comprises pathological processes of the small vessels in the br...
Heye, Anna K Thrippleton, Michael J Armitage, Paul A Valdes Hernandez, Maria Del C Makin, Stephen D ...
PurposeIncreased blood-brain barrier (BBB) permeability has been shown to play a significant role in...
Purpose: Dynamic contrast-enhanced (DCE) MRI can be used to measure blood-brain barrier (BBB) leakag...
Purpose: Dynamic contrast-enhanced (DCE) MRI can be used to measure blood-brain barrier (BBB) leakag...
Purpose: Dynamic contrast-enhanced (DCE) MRI can be used to measure blood-brain barrier (BBB) leakag...
Cerebral small vessel disease (SVD) is a common cause of strokes and dementia. The pathogenesis of ...
Objective: As blood-brain barrier (BBB) dysfunction may occur in normal aging but may also play a pi...
PURPOSE: Cerebral small vessel disease (cSVD) involves several pathologies affecting the small vesse...
BACKGROUND AND PURPOSE: Dynamic contrast-enhanced MRI (DCE-MRI) can be employed to assess the blood-...
PURPOSE: Dynamic contrast-enhanced (DCE) -MRI with Patlak model analysis is increasingly used to qua...
Blood–brain barrier (BBB) leakage can be measured using dynamic contrast‐enhanced magnetic resonance...
There is evidence that subtle breakdown of the blood–brain barrier (BBB) is a pathophysiological com...
Cerebral small vessel disease (cSVD) comprises pathological processes of the small vessels in the br...
Background Main aim was assessment of regional blood–brain barrier (BBB) function by dynamic contras...
Cerebral small vessel disease (cSVD) comprises pathological processes of the small vessels in the br...
Heye, Anna K Thrippleton, Michael J Armitage, Paul A Valdes Hernandez, Maria Del C Makin, Stephen D ...