Design of and technical challenges involved in a framework for multicentric radiotherapy treatment planning studies
- Roelofs, Erik
- Persoon, Lucas
- Qamhiyeh, Sima
- Verhaegen, Frank
- De Ruysscher, Dirk
- Scholz, Michael
- Iancu, Gheorghe
- Engelsman, Martijn
- Rasch, Coen R.
- Zijp, Lambert
- De Meerleer, Gert
- Coghe, Marc
- Langendijk, Johannes A.
- Schilstra, Cornelis
- Pijls-Johannesma, Madelon
- Lambin, Philippe
DOIAbstract
This report introduces a framework for comparing radiotherapy treatment planning in multicentric in silico clinical trials. Quality assurance, data incompatibility, transfer and storage issues, and uniform analysis of results are discussed. The solutions that are given provide a useful guide for the set-up of future multicentric planning studies or public repositories of high quality data
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