Evaluation of One-Sample Testing of Self-Obtained Vaginal Swabs and First Catch Urine Samples Separately and in Combination for the Detection of Chlamydia trachomatis by Two Amplified DNA Assays in Women Visiting a Sexually Transmitted Disease Clinic

This study evaluates the performance of self-obtained vaginal swabs (SVS)/first-catch urine (FCU) combination samples in comparison to testing FCU or SVS alone. The Chlamydia trachomatis detection rate for the SVS, FCU, and SVS/FCU combination were 94%, 90%, and 94%, respectively. Self-obtained vaginal swabs are therefore the specimen of choice for Chlamydia trachomatis Nucleic Acid Amplification Tests in females