Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identification of the antioxidant pharmacophore.Rezk BM, Haenen GR, van der Vijgh WJ, Bast A.Department of Pharmacology and Toxicology, Faculty of Medicine, Universiteit Maastricht, P.O. Box 616, NL 6200 MD, Maastricht, The Netherlands.The presumed protective effect of folic acid on the pathogenesis of cardiovascular, hematological and neurological diseases and cancer has been associated with the antioxidant activity of folic acid. Peroxynitrite (PON) scavenging activity and inhibition of lipid peroxidation (LPO) of the physiological forms of folate and of structurally related compounds were tested. It was found that the fully reduced forms of folate, ...
The biological activities of some homeosterically related analogs of dihydrofolic acid have been exa...
1. Methylenetetrahydrofolate reductase (MTHFR) is a regulating enzyme in folate-dependant homocystei...
Folate is a water-soluble vitamin that occurs in different chemical forms distinguished by their oxi...
Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identifica...
The presumed protective effect of folic acid on the pathogenesis of cardiovascular, hematological an...
AbstractThe presumed protective effect of folic acid on the pathogenesis of cardiovascular, hematolo...
Folates have a pterine core structure and high metabolic activity due to their ability to accept ele...
Abstract: Folates are important cofactors in the transfer and utilization of one-carbon-groups and p...
Adequate levels of folates are essential for homeostasis of the organism, prevention of congenital m...
Folic acid (FA), the most oxidized and stable form of folate, is commonly used as a dietary suppleme...
The liquid-chromatographic measurement of 5-methyl-tetrahydrofolate in biological fluids is describe...
The protective role of folate in vascular disease has been related to antioxidant effects. In 45 pat...
Folate is a water-soluble B-vitamin that holds a key position in cell growth and development. By DNA...
Folic acid is the parent of a number of derivatives that are vitamins, essential for DNA and amino a...
Folic acid, an essential vitamin for mammals, is the carrier of activated one-carbon units in metabo...
The biological activities of some homeosterically related analogs of dihydrofolic acid have been exa...
1. Methylenetetrahydrofolate reductase (MTHFR) is a regulating enzyme in folate-dependant homocystei...
Folate is a water-soluble vitamin that occurs in different chemical forms distinguished by their oxi...
Tetrahydrofolate and 5-methyltetrahydrofolate are folates with high antioxidant activity. Identifica...
The presumed protective effect of folic acid on the pathogenesis of cardiovascular, hematological an...
AbstractThe presumed protective effect of folic acid on the pathogenesis of cardiovascular, hematolo...
Folates have a pterine core structure and high metabolic activity due to their ability to accept ele...
Abstract: Folates are important cofactors in the transfer and utilization of one-carbon-groups and p...
Adequate levels of folates are essential for homeostasis of the organism, prevention of congenital m...
Folic acid (FA), the most oxidized and stable form of folate, is commonly used as a dietary suppleme...
The liquid-chromatographic measurement of 5-methyl-tetrahydrofolate in biological fluids is describe...
The protective role of folate in vascular disease has been related to antioxidant effects. In 45 pat...
Folate is a water-soluble B-vitamin that holds a key position in cell growth and development. By DNA...
Folic acid is the parent of a number of derivatives that are vitamins, essential for DNA and amino a...
Folic acid, an essential vitamin for mammals, is the carrier of activated one-carbon units in metabo...
The biological activities of some homeosterically related analogs of dihydrofolic acid have been exa...
1. Methylenetetrahydrofolate reductase (MTHFR) is a regulating enzyme in folate-dependant homocystei...
Folate is a water-soluble vitamin that occurs in different chemical forms distinguished by their oxi...