Cardiovascular diseases in the digital health era: A translational approach from the lab to the clinic

This article belongs to the Special Issue Bioinformatics: Present and Future BiotechnologyTranslational science has been introduced as the nexus among the scientific and the clinical field, which allows researchers to provide and demonstrate that the evidence-based research can connect the gaps present between basic and clinical levels. This type of research has played a major role in the field of cardiovascular diseases, where the main objective has been to identify and transfer potential treatments identified at preclinical stages into clinical practice. This transfer has been enhanced by the intromission of digital health solutions into both basic research and clinical scenarios. This review aimed to identify and summarize the most important translational advances in the last years in the cardiovascular field together with the potential challenges that still remain in basic research, clinical scenarios, and regulatory agencies.Supported in part by the Instituto de Salud Carlos III (PI16/01123, DTS16/0160, PI17/01059, PI19/00161, PI20/01618, DTS21/00064 and PI18/01895, Red TERCEL RETIC RD16/0011/0029) and the project RICORS "RD21/0017; TERAV" (Group: 002). The Regional Government of Madrid (S2017/BMD-3962, Avancell-CM); Spanish Ministry of Science and Innovation (CIBERCV), and European Union's H2020 Program under grant agreement No. 874827 (BRAV3)