Response of lipid bilayers to external mechanical stimuli is an active area of research with implications for fundamental and synthetic cell biology. However, there is a lack of tools for systematically imposing mechanical strains and non-invasively mapping out interfacial (membrane) stress distributions on lipid bilayers. In this article, we report a miniature platform to manipulate model cell membranes in the form of droplet interface bilayers (DIBs), and non-invasively measure spatio-temporally resolved interfacial stresses using two photon fluorescence lifetime imaging of an interfacially active molecular flipper (Flipper-TR). We established the effectiveness of the developed framework by investigating interfacial stresses accompanying ...
Droplet interface bilayers (DIBs) provide an exciting new platform for the study of membrane protein...
In this thesis an experimental model for the interface between the cell membrane and the supporting ...
Droplet Interface Bilayers (DIBs) have a number of attributes that distinguish them from conventiona...
For the past decade, droplet interface bilayers (DIBs) have had an increased prevalence in biomolecu...
For the past decade, droplet interface bilayers (DIBs) have had an increased prevalence in biomolecu...
For the past decade, droplet interface bilayers (DIBs) have had an increased prevalence in biomolecu...
Lipid membranes are commonly confined to adjacent subcellular structures or to artificial substrates...
A new rheological droplet interface bilayer (rheo-DIB) device is presented as a tool to apply shear ...
Much effort has been devoted to lipid bilayers and nanovesicles with a compositional asymmetry betwe...
Cells and organelles are delimited by lipid bilayers in which high deformability is essential to man...
We examine here the properties of lipid bilayers coupled to deformable substrates. We show that by c...
Single-channel recordings (SCR) and single-molecule Fluorescence (SMF) are invaluable tools for stud...
The spatiotemporal organization of membrane proteins is implicated in cellular trafficking, signalli...
This work describes research aimed at improving the droplet interface bilayer (DIB) platform for cre...
Biological membranes are lamellar structures composed of two leaflets capable of supporting differen...
Droplet interface bilayers (DIBs) provide an exciting new platform for the study of membrane protein...
In this thesis an experimental model for the interface between the cell membrane and the supporting ...
Droplet Interface Bilayers (DIBs) have a number of attributes that distinguish them from conventiona...
For the past decade, droplet interface bilayers (DIBs) have had an increased prevalence in biomolecu...
For the past decade, droplet interface bilayers (DIBs) have had an increased prevalence in biomolecu...
For the past decade, droplet interface bilayers (DIBs) have had an increased prevalence in biomolecu...
Lipid membranes are commonly confined to adjacent subcellular structures or to artificial substrates...
A new rheological droplet interface bilayer (rheo-DIB) device is presented as a tool to apply shear ...
Much effort has been devoted to lipid bilayers and nanovesicles with a compositional asymmetry betwe...
Cells and organelles are delimited by lipid bilayers in which high deformability is essential to man...
We examine here the properties of lipid bilayers coupled to deformable substrates. We show that by c...
Single-channel recordings (SCR) and single-molecule Fluorescence (SMF) are invaluable tools for stud...
The spatiotemporal organization of membrane proteins is implicated in cellular trafficking, signalli...
This work describes research aimed at improving the droplet interface bilayer (DIB) platform for cre...
Biological membranes are lamellar structures composed of two leaflets capable of supporting differen...
Droplet interface bilayers (DIBs) provide an exciting new platform for the study of membrane protein...
In this thesis an experimental model for the interface between the cell membrane and the supporting ...
Droplet Interface Bilayers (DIBs) have a number of attributes that distinguish them from conventiona...