peer reviewedBackground and aim. Cognitive aging models propose that cognitive resources available decrease with age, and that older people experience a more pronounced decline in performance over time. Mental fatigue is also known to negatively impact cognitive performance. How available cognitive resources interact with fatigue level across the lifespan remains largely unexplored. Our objective is to identify and compare the effects of an induced mental fatigue state on cognitive performance in young, middle-aged, and older participants. Methods. 43 young, 25 middle-aged and 19 older people performed a 32-min mental fatigue induction task in condition of high or low cognitive load (HCL/LCL). Cognitive load was modulated by the stimuli ...