Calcium ions (Ca2+) are involved in almost all neuronal functions, providing the link between electrical signals and cellular activity. This work examines the mechanisms by which a neuron can regulate the movement and sequestration of Ca2+ through specific channels such that this ubiquitous ion can encode specific functions. My initial focus was using intracellular calcium ([Ca2+]i) imaging techniques to study the influence of the inhibition of specific voltage gated calcium channels (VGCC) by ethanol on a depolarization induced rise in [Ca2+]i in neurohypophysial nerve terminals. This research took an unexpected turn when I observed an elevation of [Ca2+]i during perfusion with ethanol containing solutions. Control experiments showed this ...
Our understanding of calcium's role in cerebral ischemia continues to evolve from the initial recogn...
It has previously been shown that the inhibition of L-type calcium channels (LTCCs) decreases alcoho...
AbstractNeuronal voltage-gated calcium channels generate rapid, transient intracellular calcium sign...
Treball final de Grau en Psicologia. Codi: PS1048. Curs acadèmic 2014-2015Alcohol is the most consum...
We report that intracellular calcium levels rise in mammalian neurosecretory terminals and in cultur...
Tolerance is an important element of drug addiction and provides a model for understanding neuronal ...
Ingestion of ethanol results in a decreased level of plasma vasopressin, which appears to be caused ...
Calcium (Ca2+) has been characterized as one of the most ubiquitous, universal and versatile intrace...
Chronic ethanol exposure increases the density of N-type calcium channels in brain. We report that e...
AbstractChronic ethanol exposure increases the density of N-type calcium channels in brain. We repor...
Calcium flux through voltage gate calcium channels (VGCC) is involved in many neuronal processes suc...
There is a clear need for new therapeutics to treat alcoholism. Here, we test our hypothesis that se...
Ethanol modulation of calcium- and voltage-gated potassium (slo1) channels alters neuronal excitabil...
The present study is composed of two relatively independent analyses of ethanol and fatty acids as p...
This paper is a review, based largely though not exclusively on work from the authors' research grou...
Our understanding of calcium's role in cerebral ischemia continues to evolve from the initial recogn...
It has previously been shown that the inhibition of L-type calcium channels (LTCCs) decreases alcoho...
AbstractNeuronal voltage-gated calcium channels generate rapid, transient intracellular calcium sign...
Treball final de Grau en Psicologia. Codi: PS1048. Curs acadèmic 2014-2015Alcohol is the most consum...
We report that intracellular calcium levels rise in mammalian neurosecretory terminals and in cultur...
Tolerance is an important element of drug addiction and provides a model for understanding neuronal ...
Ingestion of ethanol results in a decreased level of plasma vasopressin, which appears to be caused ...
Calcium (Ca2+) has been characterized as one of the most ubiquitous, universal and versatile intrace...
Chronic ethanol exposure increases the density of N-type calcium channels in brain. We report that e...
AbstractChronic ethanol exposure increases the density of N-type calcium channels in brain. We repor...
Calcium flux through voltage gate calcium channels (VGCC) is involved in many neuronal processes suc...
There is a clear need for new therapeutics to treat alcoholism. Here, we test our hypothesis that se...
Ethanol modulation of calcium- and voltage-gated potassium (slo1) channels alters neuronal excitabil...
The present study is composed of two relatively independent analyses of ethanol and fatty acids as p...
This paper is a review, based largely though not exclusively on work from the authors' research grou...
Our understanding of calcium's role in cerebral ischemia continues to evolve from the initial recogn...
It has previously been shown that the inhibition of L-type calcium channels (LTCCs) decreases alcoho...
AbstractNeuronal voltage-gated calcium channels generate rapid, transient intracellular calcium sign...