Long-lived cancer stem cells (CSCs) with indefinite proliferative potential have been identified in multiple epithelial cancer types. These cells are likely derived from transformed adult stem cells and are thought to share many characteristics with their parental population, including a quiescent slow-cycling phenotype. Various label-retaining techniques have been used to identify normal slow cycling adult stem cell populations and offer a unique methodology to functionally identify and isolate cancer stem cells. The quiescent nature of CSCs represents an inherent mechanism that at least partially explains chemotherapy resistance and recurrence in posttherapy cancer patients. Isolating and understanding the cell cycle regulatory mechanisms...
The Cancer Stem Cells (CSC) hypothesis is based on three fundamental ideas: 1) the similarities in t...
The Cancer Stem Cells (CSC) hypothesis is based on three fundamental ideas: 1) the similarities in t...
To date two questions that remain unanswered regarding cancer are the following: i) how is it initia...
Long-lived cancer stem cells (CSCs) with indefinite proliferative potential have been identified in ...
Tumor recurrence after chemotherapy is a major cause of patient morbidity and mortality. Recurrences...
Background: Quiescent/slow cycling cells have been identified in several tumors and correlated with ...
BACKGROUND: Quiescent/slow cycling cells have been identified in several tumors and correlated with ...
Abstract: Highly malignant tumors mostly consist of rapidly proliferating cells. However, tumors als...
The classic hallmarks of cancer are a poorly differentiated phenotype, and a cellular and genetic he...
To date two questions that remain unanswered regarding cancer are the following: i) how is it initia...
Cancer stem cells (CSCs) are a specific subpopulation of tumor cells that selectively possess tumor ...
The Cancer Stem Cells (CSC) hypothesis is based on three fundamental ideas: 1) the similarities in t...
Tumor recurrence after chemotherapy is a major cause of patient morbidity and mortality. Recurrences...
Cancer stem cells (CSCs) are the pathological counterpart of normal somatic tissue stem cells. They ...
Summary: Recent data suggest that therapy-resistant quiescent cancer stem cells (qCSCs) are the sour...
The Cancer Stem Cells (CSC) hypothesis is based on three fundamental ideas: 1) the similarities in t...
The Cancer Stem Cells (CSC) hypothesis is based on three fundamental ideas: 1) the similarities in t...
To date two questions that remain unanswered regarding cancer are the following: i) how is it initia...
Long-lived cancer stem cells (CSCs) with indefinite proliferative potential have been identified in ...
Tumor recurrence after chemotherapy is a major cause of patient morbidity and mortality. Recurrences...
Background: Quiescent/slow cycling cells have been identified in several tumors and correlated with ...
BACKGROUND: Quiescent/slow cycling cells have been identified in several tumors and correlated with ...
Abstract: Highly malignant tumors mostly consist of rapidly proliferating cells. However, tumors als...
The classic hallmarks of cancer are a poorly differentiated phenotype, and a cellular and genetic he...
To date two questions that remain unanswered regarding cancer are the following: i) how is it initia...
Cancer stem cells (CSCs) are a specific subpopulation of tumor cells that selectively possess tumor ...
The Cancer Stem Cells (CSC) hypothesis is based on three fundamental ideas: 1) the similarities in t...
Tumor recurrence after chemotherapy is a major cause of patient morbidity and mortality. Recurrences...
Cancer stem cells (CSCs) are the pathological counterpart of normal somatic tissue stem cells. They ...
Summary: Recent data suggest that therapy-resistant quiescent cancer stem cells (qCSCs) are the sour...
The Cancer Stem Cells (CSC) hypothesis is based on three fundamental ideas: 1) the similarities in t...
The Cancer Stem Cells (CSC) hypothesis is based on three fundamental ideas: 1) the similarities in t...
To date two questions that remain unanswered regarding cancer are the following: i) how is it initia...