Selenium deficiency in rats is characterized by elevated serum T4 and decreased serum T3 concentrations, and low liver type I (5\u27D-I) and brain type II (5\u27D-II) iodothyronine 5\u27-deiodinase activities. These findings are partially explained by the demonstration that type I 5\u27D is a selenoprotein; however, 5\u27D-II does not contain selenium. Since 5\u27D-II varies inversely with serum T4 concentrations, and serum T4 is elevated in selenium deficiency, the decreased cerebrocortical 5\u27D-II activity may be secondary to the increased serum T4 levels. To determine the mechanism(s) by which selenium influences 5\u27D-II activity, we examined the effects of altered selenium intake on brain 5\u27D-II levels and enzyme turnover in euth...
textabstractThe hypothesis tested was whether marginal iodine deficiency for a period of 6 wk affect...
Selenium (Se) is an essential trace element and plays many important biological roles in the body. S...
Essential trace elements are functional, structural and regulatory components of a number of bio-mol...
In selenium-deficient rats, peripheral T4 to T3 conversion is markedly decreased due to the loss of ...
(Requests for oVprints should be addressed to J R Arthur) Selenium deficiency causes further impairm...
In the rat, selenium deficiency causes a near-complete loss of the selenoenzyme type I 5\u27-deiodin...
Selenium deficiency and propylthiouracil (PTU) treatment both decrease hepatic type I T4 5\u27-deiod...
Impaired expression of selenium-containing proteins leads to perturbed thyroid hormone (TH) levels, ...
Both selenium, as an effector and regulator of antioxidative enzymes activity, and thyroid hormones ...
The effect of selenium deficiency associated with various iodide intake was investigated in rats in ...
ABSTRACT Studies were performed to assess the role of combined selenium and iodine deficiency in the...
1. Iodothyronine 5'-deiodinase, which is mainly responsible for peripheral triiodothyronine (T-3) pr...
In rats, the respective contribution of the thyroid and peripheral tissues to the pool of T3 remains...
International audienceThis study was designed to investigate the effects of di-(2-ethylhexyl) phthal...
Selenium and iodine are the two central trace elements for the homeostasis of thyroid hormones but a...
textabstractThe hypothesis tested was whether marginal iodine deficiency for a period of 6 wk affect...
Selenium (Se) is an essential trace element and plays many important biological roles in the body. S...
Essential trace elements are functional, structural and regulatory components of a number of bio-mol...
In selenium-deficient rats, peripheral T4 to T3 conversion is markedly decreased due to the loss of ...
(Requests for oVprints should be addressed to J R Arthur) Selenium deficiency causes further impairm...
In the rat, selenium deficiency causes a near-complete loss of the selenoenzyme type I 5\u27-deiodin...
Selenium deficiency and propylthiouracil (PTU) treatment both decrease hepatic type I T4 5\u27-deiod...
Impaired expression of selenium-containing proteins leads to perturbed thyroid hormone (TH) levels, ...
Both selenium, as an effector and regulator of antioxidative enzymes activity, and thyroid hormones ...
The effect of selenium deficiency associated with various iodide intake was investigated in rats in ...
ABSTRACT Studies were performed to assess the role of combined selenium and iodine deficiency in the...
1. Iodothyronine 5'-deiodinase, which is mainly responsible for peripheral triiodothyronine (T-3) pr...
In rats, the respective contribution of the thyroid and peripheral tissues to the pool of T3 remains...
International audienceThis study was designed to investigate the effects of di-(2-ethylhexyl) phthal...
Selenium and iodine are the two central trace elements for the homeostasis of thyroid hormones but a...
textabstractThe hypothesis tested was whether marginal iodine deficiency for a period of 6 wk affect...
Selenium (Se) is an essential trace element and plays many important biological roles in the body. S...
Essential trace elements are functional, structural and regulatory components of a number of bio-mol...