Stimulation of confluent monolayers of nondividing WI-38 cells to proliferate is accompanied by a doubling in the rate of phosphorylation of nonhistone chromosomal proteins during the first hour. The use of cycloheximide to inhibit protein synthesis does not appear to affect phosphorylation of the nonhistones. Nondividing and serum-stimulated cells exhibit qualitative differences in the phosphorylation and dephosphorylation of individual polypeptide peaks resolved by polyacrylamide gel electrophoresis. These results are consistent with other evidence implicating nonhistone protein phosphorylation as an early event involved in the activation of transcription occurring during cell proliferation
The composition and metabolism of nonhistone chromosomal proteins associated with the genome of norm...
To ascertain the activity and substrate specificity of nuclear protein kinases during various stages...
PhDBiochemistryUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.l...
Stimulation of confluent monolayers of nondividing WI-38 cells to proliferate is accompanied by a do...
Serum stimulation of early as well as late passages of nondividing WI-38 human diploid fibroblasts t...
Because the phosphorylation of non-histone proteins has been suggested to play a role in the regulat...
The phosphorylation of non-histone chromatin proteins in synchronized HeLa S3 cells was studied in 5...
Nuclear and cytoplasmic proteins synthesised by mouse lymphocytes stimulated in vitro by the B lymph...
The synthesis of non-histone chromatin proteins and nucleoplasmic proteins has been followed during ...
Stimulation of mouse lymphocytes with the B lymphocyte specific mitogen lipopolysaccharide results i...
The turnover of nonhistone chromosomal proteins and their phosphate groups was compared in normal an...
Histone gene expression was studied during the cell cycle of continuously dividing HeLa S3-cells and...
Non-histone chromosomal proteins are phosphorylated and dephosphorylated within the intact nucleus b...
The composition and metabolism of nonhistone chromosomal proteins associated with the genome of norm...
When G0 cells are stimulated to proliferate, a sequence of biochemical events occurs that eventually...
The composition and metabolism of nonhistone chromosomal proteins associated with the genome of norm...
To ascertain the activity and substrate specificity of nuclear protein kinases during various stages...
PhDBiochemistryUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.l...
Stimulation of confluent monolayers of nondividing WI-38 cells to proliferate is accompanied by a do...
Serum stimulation of early as well as late passages of nondividing WI-38 human diploid fibroblasts t...
Because the phosphorylation of non-histone proteins has been suggested to play a role in the regulat...
The phosphorylation of non-histone chromatin proteins in synchronized HeLa S3 cells was studied in 5...
Nuclear and cytoplasmic proteins synthesised by mouse lymphocytes stimulated in vitro by the B lymph...
The synthesis of non-histone chromatin proteins and nucleoplasmic proteins has been followed during ...
Stimulation of mouse lymphocytes with the B lymphocyte specific mitogen lipopolysaccharide results i...
The turnover of nonhistone chromosomal proteins and their phosphate groups was compared in normal an...
Histone gene expression was studied during the cell cycle of continuously dividing HeLa S3-cells and...
Non-histone chromosomal proteins are phosphorylated and dephosphorylated within the intact nucleus b...
The composition and metabolism of nonhistone chromosomal proteins associated with the genome of norm...
When G0 cells are stimulated to proliferate, a sequence of biochemical events occurs that eventually...
The composition and metabolism of nonhistone chromosomal proteins associated with the genome of norm...
To ascertain the activity and substrate specificity of nuclear protein kinases during various stages...
PhDBiochemistryUniversity of Michigan, Horace H. Rackham School of Graduate Studieshttp://deepblue.l...