As cell size decreases during the reductive divisions of early development, intracellular structures must shrink to fit. In this issue of Developmental Cell, Lacroix et al. (2018) identify a conserved mechanism of spindle scaling in nematode and sea urchin embryos whereby spindle microtubule polymerization rates decrease as development proceeds
Background Cellular structures such as the nucleus, Golgi, centrioles, and spindle show remarkable ...
Cells need to regulate the size and shape of their organelles for proper function. For example, the ...
SummaryBackgroundThe pole-to-pole distance of the metaphase spindle is reasonably constant in a give...
Successive cell divisions during embryonic cleavage create increasingly smaller cells, so intracellu...
International audienceSuccessive cell divisions during embryonic cleavage create increasingly smalle...
Cell division in all eukaryotes depends on function of the spindle, a microtubule-based structure th...
Cellular organelles such as the mitotic spindle adjust their size to the dimensions of the cell. It ...
SummaryCell division in all eukaryotes depends on function of the spindle, a microtubule-based struc...
Cellular organelles such as the mitotic spindle adjust their size to the dimensions of the cell. It ...
During cell division, the mitotic spindle, a macromolecular structure primarily comprised of microtu...
SummaryA new study investigating the origins of diversity in the structure of the mitotic spindle in...
SummaryThe spindle assembly checkpoint (SAC) delays mitotic progression when chromosomes are not pro...
Early development of many animals is characterized by rapid cleavages that dramatically decrease cel...
The spindle assembly checkpoint (SAC) delays mitotic progression when chromosomes are not properly a...
Regulation of size and growth is a fundamental problem in biology and often closely related to funct...
Background Cellular structures such as the nucleus, Golgi, centrioles, and spindle show remarkable ...
Cells need to regulate the size and shape of their organelles for proper function. For example, the ...
SummaryBackgroundThe pole-to-pole distance of the metaphase spindle is reasonably constant in a give...
Successive cell divisions during embryonic cleavage create increasingly smaller cells, so intracellu...
International audienceSuccessive cell divisions during embryonic cleavage create increasingly smalle...
Cell division in all eukaryotes depends on function of the spindle, a microtubule-based structure th...
Cellular organelles such as the mitotic spindle adjust their size to the dimensions of the cell. It ...
SummaryCell division in all eukaryotes depends on function of the spindle, a microtubule-based struc...
Cellular organelles such as the mitotic spindle adjust their size to the dimensions of the cell. It ...
During cell division, the mitotic spindle, a macromolecular structure primarily comprised of microtu...
SummaryA new study investigating the origins of diversity in the structure of the mitotic spindle in...
SummaryThe spindle assembly checkpoint (SAC) delays mitotic progression when chromosomes are not pro...
Early development of many animals is characterized by rapid cleavages that dramatically decrease cel...
The spindle assembly checkpoint (SAC) delays mitotic progression when chromosomes are not properly a...
Regulation of size and growth is a fundamental problem in biology and often closely related to funct...
Background Cellular structures such as the nucleus, Golgi, centrioles, and spindle show remarkable ...
Cells need to regulate the size and shape of their organelles for proper function. For example, the ...
SummaryBackgroundThe pole-to-pole distance of the metaphase spindle is reasonably constant in a give...