External genitalia development occurs through a combination of hormone independent, hormone dependent, and endocrine pathways. Perturbation of these pathways can lead to abnormal external genitalia development. We review human and animal mechanisms of normal and abnormal external genitalia development, and we evaluate abnormal mechanisms that lead to hypospadias. We also discuss recent laboratory findings that further our understanding of animal models of hypospadias
The mammalian female reproductive tract develops from the Mullerian ducts which differentiate, in a ...
Abstract Background Hypospadias is a common inborn error of the male urethral development, for which...
The development of human internal and external reprodictive organs is regulated on chromosomal, gene...
The Jost hypothesis states that androgens are necessary for normal development of the male external ...
The incidence of congenital malformation of the urogenital system is second only to that of the card...
Hypospadias is a congenital abnormality of the penile urethra with an incidence of approximately 1:2...
Hypospadias is one of the most common congenital anomalies in the United States, occurring in approx...
Hypospadias is a defect in penile urethral closure that occurs in approximately 1/150 live male birt...
Hypospadias is a congenital abnormality of the penile urethra with an incidence of approximately 1:2...
© 2017 Dr. Tiffany PhillipsHypospadias, the ectopic placement of the urethral meatus along the ventr...
The molecular mechanisms underlying the development of the external genitalia in mammals have been v...
The common view on penile development is that it is androgen-dependent, based first and foremost on ...
International audienceDuring the last decade, a tremendous amount of work has been devoted to the st...
© 2020 Luke Christopher GoversHypospadias is the most common persisting congenital abnormality in ma...
International audienceThe mammalian female reproductive tract develops from the Mullerian ducts whic...
The mammalian female reproductive tract develops from the Mullerian ducts which differentiate, in a ...
Abstract Background Hypospadias is a common inborn error of the male urethral development, for which...
The development of human internal and external reprodictive organs is regulated on chromosomal, gene...
The Jost hypothesis states that androgens are necessary for normal development of the male external ...
The incidence of congenital malformation of the urogenital system is second only to that of the card...
Hypospadias is a congenital abnormality of the penile urethra with an incidence of approximately 1:2...
Hypospadias is one of the most common congenital anomalies in the United States, occurring in approx...
Hypospadias is a defect in penile urethral closure that occurs in approximately 1/150 live male birt...
Hypospadias is a congenital abnormality of the penile urethra with an incidence of approximately 1:2...
© 2017 Dr. Tiffany PhillipsHypospadias, the ectopic placement of the urethral meatus along the ventr...
The molecular mechanisms underlying the development of the external genitalia in mammals have been v...
The common view on penile development is that it is androgen-dependent, based first and foremost on ...
International audienceDuring the last decade, a tremendous amount of work has been devoted to the st...
© 2020 Luke Christopher GoversHypospadias is the most common persisting congenital abnormality in ma...
International audienceThe mammalian female reproductive tract develops from the Mullerian ducts whic...
The mammalian female reproductive tract develops from the Mullerian ducts which differentiate, in a ...
Abstract Background Hypospadias is a common inborn error of the male urethral development, for which...
The development of human internal and external reprodictive organs is regulated on chromosomal, gene...