Add to ORKGOptical modulation of proteins provides superior spatiotemporal resolution for understanding biological processes, and photoswitches built on light-sensitive proteins have been significantly advancing neuronal and cellular studies. Small molecule photoswitches could complement protein-based switches by mitigating potential interference and affording high specificity for modulation sites. However, genetic encodability and responsiveness to nonultraviolet light, two desired properties possessed by protein photoswitches, are challenging to be engineered into small molecule photoswitches. Here we developed a small molecule photoswitch that can be genetically installed onto proteins in situ and controlled by visible light. A pentafluoro azobenze...
Proteins have the potential to serve as nanomachines with well-controlled structural movements, and ...
In recent years, interest in controlling protein function with light has increased. Light offers a n...
The last few years have witnessed significant advances in the use of light as a stimulus to control ...
Optical modulation of proteins provides superior spatiotemporal resolution for understanding biologi...
The ability to reversibly control protein structure and function with light would offer high spatiot...
Over the past decade, photoswitchable molecules have been emerging as attractive tools for investiga...
Life relies on a myriad of carefully orchestrated processes, in which proteins and their direct inte...
Many biological processes are governed by protein activities that are spatially and temporally regul...
Many biological processes are governed by protein activities that are spatially and temporally regul...
Nature provides an array of proteins that change conformation in response to light. The discovery of...
Nature provides an array of proteins that change conformation in response to light. The discovery of...
Nature provides an array of proteins that change conformation in response to light. The discovery of...
Nature provides an array of proteins that change conformation in response to light. The discovery of...
Light-switchable proteins are being used increasingly to understand and manipulate complex molecular...
Light-switchable proteins are being used increasingly to understand and manipulate complex molecular...
Proteins have the potential to serve as nanomachines with well-controlled structural movements, and ...
In recent years, interest in controlling protein function with light has increased. Light offers a n...
The last few years have witnessed significant advances in the use of light as a stimulus to control ...
Optical modulation of proteins provides superior spatiotemporal resolution for understanding biologi...
The ability to reversibly control protein structure and function with light would offer high spatiot...
Over the past decade, photoswitchable molecules have been emerging as attractive tools for investiga...
Life relies on a myriad of carefully orchestrated processes, in which proteins and their direct inte...
Many biological processes are governed by protein activities that are spatially and temporally regul...
Many biological processes are governed by protein activities that are spatially and temporally regul...
Nature provides an array of proteins that change conformation in response to light. The discovery of...
Nature provides an array of proteins that change conformation in response to light. The discovery of...
Nature provides an array of proteins that change conformation in response to light. The discovery of...
Nature provides an array of proteins that change conformation in response to light. The discovery of...
Light-switchable proteins are being used increasingly to understand and manipulate complex molecular...
Light-switchable proteins are being used increasingly to understand and manipulate complex molecular...
Proteins have the potential to serve as nanomachines with well-controlled structural movements, and ...
In recent years, interest in controlling protein function with light has increased. Light offers a n...
The last few years have witnessed significant advances in the use of light as a stimulus to control ...