Apparatus for tubulus detection from a tissue biopsy

The present invention relates to an apparatus (10) for tubulus detection from a tissue biopsy. It is described to provide (210) a plurality of 2D images of a tissue biopsy, wherein each 2D image corresponds to a different depth position in the tissue biopsy, and wherein each 2D image comprises image data of the tissue biopsy. A measure of a local variation of intensity is determined (220) in the image data of the tissue biopsy in a region of at least one 2D image. At least part of a tubulus is located (230) in the region of the at least one 2D image on the basis of the determined measure of the local variation of intensity. The locating (230) involves determining (240) locations in the region of the at least one 2D image where the measure of the local variation in intensity is below a threshold. Data representative of the location of the at least part of the tubulus in the region of the at least one 2D image are output (250)