Since it was theorized more than 50 years ago, nanotechnology has become the perfect boost for existing old technologies. The unique properties exhibited by materials at these scales have a potential to improve the performance of mature oil fields along with enhanced oil recovery (EOR) processes. Regarding polymer flooding, the influence of the (macro) molecules’ architecture on the fluid properties has been lately stressed. This chapter presents the numerical simulation of the combination of both agents in a single, combined recovery process. The presence of the nanoparticles affects the rheological behavior and the rock’s wettability, increasing the organic phase mobility. Undesirable effects such as (nano) particle aggregation and sedime...