The functional decline that is observed in HSCs upon aging is attributed mainly to cell intrinsic factors that regulate quiescence, self-renewal and differentiation. MicroRNAs (miRs) have an indispensable role in the regulation of HSCs and have been shown to also regulate processes related to tissue aging in specific cell types. Here we discuss the role of miRs in the regulation of HSC self-renewal and differentiation throughout life and its implications for future research.</p
MicroRNAs (miRs) are small noncoding RNAs that regulate gene expression posttranscriptionally by bin...
Hematopoietic stem cells (HSCs) ensure a balanced production of all blood cells throughout life. As ...
Hematopoietic stem cells (HSCs), located in bone marrow, sustain life time blood production by self-...
The functional decline that is observed in HSCs upon aging is attributed mainly to cell intrinsic fa...
Aging is a biological process determined through time-related cellular and functional impairments, l...
Hematopoietic stem cells (HSCs) are the adult stem cells in the bone marrow that are responsible for...
Abstract Restoration of tissue homeostasis by controlling stem cell aging is a promising therapeutic...
Peter van Galen focuses on understanding the determinants that maintain the stem cell state. Using h...
SummaryMicroRNAs are critical post-transcriptional regulators of hematopoietic cell-fate decisions, ...
MicroRNAs are critical post-transcriptional regulators of hematopoietic cell-fate decisions, though ...
MicroRNAs are critical post-transcriptional regulators of hematopoietic cell-fate decisions, though ...
MicroRNAs (miRs) are small noncoding RNAs that regulate gene expression posttranscriptionally by bin...
Hematopoietic stem cells (HSCs) ensure a balanced production of all blood cells throughout life. As ...
Hematopoietic stem cells (HSCs), located in bone marrow, sustain life time blood production by self-...
The functional decline that is observed in HSCs upon aging is attributed mainly to cell intrinsic fa...
Aging is a biological process determined through time-related cellular and functional impairments, l...
Hematopoietic stem cells (HSCs) are the adult stem cells in the bone marrow that are responsible for...
Abstract Restoration of tissue homeostasis by controlling stem cell aging is a promising therapeutic...
Peter van Galen focuses on understanding the determinants that maintain the stem cell state. Using h...
SummaryMicroRNAs are critical post-transcriptional regulators of hematopoietic cell-fate decisions, ...
MicroRNAs are critical post-transcriptional regulators of hematopoietic cell-fate decisions, though ...
MicroRNAs are critical post-transcriptional regulators of hematopoietic cell-fate decisions, though ...
MicroRNAs (miRs) are small noncoding RNAs that regulate gene expression posttranscriptionally by bin...
Hematopoietic stem cells (HSCs) ensure a balanced production of all blood cells throughout life. As ...
Hematopoietic stem cells (HSCs), located in bone marrow, sustain life time blood production by self-...
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