Failing or missing teeth in the aesthetic region of the maxilla (1st premolar to 1st premolar) create a difficult challenge for patients and dental professionals, because of the aesthetic demands and patient’s expectations. This PhD thesis discusses the complexity of implant treatment in the maxillary aesthetic region (chapter 1). The overall aim of the studies described in this thesis was to assess the outcome of several implant treatment strategies for one or two failing or missing teeth in the maxillary aesthetic region:- Treatment of one failing tooth with immediate implant placement and provisionalization (chapter 2);- Treatment of one failing tooth with immediate implant placement and provisionalization, with or without a connective t...