A synthetic methodology for the synthesis of 13,14-seco-steroids with substituents at C-14 and C-17 is described. The approach involves Grob fragmentation of 14ß-hydroxy-17ß-tosylates, hydroboration–oxidation of the intermediate ¿13(17)-olefin, and hydride reduction of the 14-ketone. An unambiguous structural assignment of (13R,14S,17S)-14,17-diacetoxy-3-methoxy-7a-methyl-13,14-secoestra-1,3,5(10)-triene was determined by X-ray analysis
The first section of this thesis presents a review of the literature on hormones and anti-hormones, ...
A short and efficient procedure has been developed for the synthesis of C,D-cis coupled steroid and ...
A number of 5,10-seco analogs of testosterone has been synthesized starting from products of the rad...
A synthetic methodology for the synthesis of 13,14-seco-steroids with substituents at C-14 and C-17 ...
The synthesis of 13,14-seco steroids starting from easily available (13S)-13-iodo-6-methoxy-3,5-cycl...
A number of testosterone analogs with a 13,14-secosteroidal fragment have been prepared from (13S)-1...
Oxidations of 14 alpha-hydroxy-5 alpha-cholestan-3 beta-yl acetate (5) with lead tetraacetate under ...
Oxidations of 14α‐hydroxy‐5α‐cholestan‐3β‐yl acetate (5) with lead tetraacetate under thermal or pho...
This thesis is concerned with an approach to the synthesis of the C/D ring system and side chain of ...
In this paper a synthetic pathway to the modified 5,10:13,14-bisfragmentation cholestane derivatives...
The radical oxidation of 14a-hydroxy steroids with various functional groups at C-17 was studied. Le...
New, short, and flexible procedures have been developed for syntheses of steroid and D-homo steroid ...
Three new, short, and efficient procedures have been developed for syntheses of steroid and D-homo s...
<p>Two protected 14,15-secoergostane derivatives suitable as pivotal intermediates for the synthesis...
The synthesis and identification of 12 A-ring reduced 6 alpha-(and 6 beta-)hydroxylated compounds de...
The first section of this thesis presents a review of the literature on hormones and anti-hormones, ...
A short and efficient procedure has been developed for the synthesis of C,D-cis coupled steroid and ...
A number of 5,10-seco analogs of testosterone has been synthesized starting from products of the rad...
A synthetic methodology for the synthesis of 13,14-seco-steroids with substituents at C-14 and C-17 ...
The synthesis of 13,14-seco steroids starting from easily available (13S)-13-iodo-6-methoxy-3,5-cycl...
A number of testosterone analogs with a 13,14-secosteroidal fragment have been prepared from (13S)-1...
Oxidations of 14 alpha-hydroxy-5 alpha-cholestan-3 beta-yl acetate (5) with lead tetraacetate under ...
Oxidations of 14α‐hydroxy‐5α‐cholestan‐3β‐yl acetate (5) with lead tetraacetate under thermal or pho...
This thesis is concerned with an approach to the synthesis of the C/D ring system and side chain of ...
In this paper a synthetic pathway to the modified 5,10:13,14-bisfragmentation cholestane derivatives...
The radical oxidation of 14a-hydroxy steroids with various functional groups at C-17 was studied. Le...
New, short, and flexible procedures have been developed for syntheses of steroid and D-homo steroid ...
Three new, short, and efficient procedures have been developed for syntheses of steroid and D-homo s...
<p>Two protected 14,15-secoergostane derivatives suitable as pivotal intermediates for the synthesis...
The synthesis and identification of 12 A-ring reduced 6 alpha-(and 6 beta-)hydroxylated compounds de...
The first section of this thesis presents a review of the literature on hormones and anti-hormones, ...
A short and efficient procedure has been developed for the synthesis of C,D-cis coupled steroid and ...
A number of 5,10-seco analogs of testosterone has been synthesized starting from products of the rad...