Experimental and Clinical Cardiac Beta-receptor Studies
- Anthonio, Rutger
- van Waarde, Aren
- Willemsen, Antoon T.M.
- Pruim, Jan
- van Gilst, Wiekert
- Blanksma, Paulus
- Vaalburg, Willem
- Lie, K.I.
DOIAbstract
PET imaging may provide new insights in in vivo changes of cardiac beta-adrenoceptors. Using 11C-CGP12177 and PET (CGP-PET) with standardized reorientation to 10 short axis slices, changes in beta-receptor distribution e.g. due to myocardial infarction and ischemia may be better identified and characterized. Because of its non-invasive character, PET also provides the possibility of serial measurements, and may elucidate the effect of different treatment strategies on cardiac beta-adrenoceptor density in several heart disases
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