Add to ORKGbeta-Amyloid((1-42)) peptide (beta AP) was injected into the right nucleus basalis magnocellularis (nbm) of rats. After a 14-day survival time, the acetylcholinesterase and choline acetyltransferase activities and the number of muscarinic receptors were found biochemically to be significantly reduced in the ipsilateral frontal cortices. Confirmation of these data with silver staining also revealed degeneration of the projective fibers of the nbm to the frontal cortex. These results demonstrate the cholinotoxicity of beta AP in an in vivo animal model.</p
Whereas a cardinal role for beta-amyloid protein (A beta) has been postulated as a major trigger of ...
The neurotoxic effect of amyloid-beta peptide (1-42) was investigated in cultures of neuronal tissue...
The effect of cholinergic basal forebrain lesions on immunoreactivity to somatostatin (SOM-i) and ne...
beta-Amyloid((1-42)) peptide (beta AP) was injected into the right nucleus basalis magnocellularis (...
β-Amyloid(1-42) peptide (βAP) was injected into the right nucleus basalis magnocellularis (nbm) of r...
Alzheimer's disease is the most common type of dementia with a still largely unclear etiopathology, ...
The effects on cholinergic, excitatory amino acid and neuropeptide markers in the basal forebrain of...
beta-Amyloid((1-42)) peptide (beta AP((1-42))) was injected into the medial septum of rats. After a ...
Long-term behavioral effects, changes in learning and memory functions and aberrations of cholinergi...
Alzheimer's disease is the most common type of dementia with a still largely unclear etiopathology, ...
ABSTRACT: Alzheimer’s disease is the most common type of dementia with a still largely unclear etiop...
Long-term behavioral effects, changes in learning and memory functions and aberrations of cholinergi...
Alzheimer’s disease is the most common type of dementia with a still largely unclear etiopathology. ...
Whereas a cardinal role for beta-amyloid protein (A beta) has been postulated as a major trigger of ...
The neurotoxic effect of amyloid-beta peptide (1-42) was investigated in cultures of neuronal tissue...
The effect of cholinergic basal forebrain lesions on immunoreactivity to somatostatin (SOM-i) and ne...
beta-Amyloid((1-42)) peptide (beta AP) was injected into the right nucleus basalis magnocellularis (...
β-Amyloid(1-42) peptide (βAP) was injected into the right nucleus basalis magnocellularis (nbm) of r...
Alzheimer's disease is the most common type of dementia with a still largely unclear etiopathology, ...
The effects on cholinergic, excitatory amino acid and neuropeptide markers in the basal forebrain of...
beta-Amyloid((1-42)) peptide (beta AP((1-42))) was injected into the medial septum of rats. After a ...
Long-term behavioral effects, changes in learning and memory functions and aberrations of cholinergi...
Alzheimer's disease is the most common type of dementia with a still largely unclear etiopathology, ...
ABSTRACT: Alzheimer’s disease is the most common type of dementia with a still largely unclear etiop...
Long-term behavioral effects, changes in learning and memory functions and aberrations of cholinergi...
Alzheimer’s disease is the most common type of dementia with a still largely unclear etiopathology. ...
Whereas a cardinal role for beta-amyloid protein (A beta) has been postulated as a major trigger of ...
The neurotoxic effect of amyloid-beta peptide (1-42) was investigated in cultures of neuronal tissue...
The effect of cholinergic basal forebrain lesions on immunoreactivity to somatostatin (SOM-i) and ne...