Iron deficiency in chronic heart failure:An international pooled analysis
- Klip, IJsbrand T.
- Comin-Colet, Josep
- Voors, Adriaan A.
- Ponikowski, Piotr
- Enjuanes, Cristina
- Banasiak, Waldemar
- Lok, Dirk J.
- Rosentryt, Piotr
- Torrens, Ainhoa
- Polonski, Lech
- van Veldhuisen, Dirk J.
- van der Meer, Peter
- Jankowska, Ewa A.
Publication date
April 2013
DOIAbstract
Background Iron deficiency (ID) is an emerging problem in patients with chronic heart failure (HF) and can be a potential therapeutic target. However, not much is known about the prevalence, predictors, and prognosis of ID in patients with chronic HF.Methods In an international pooled cohort comprising 1,506 patients with chronic HF, we studied the clinical associates of ID and its prognostic consequences.Results Iron deficiency (defined as a ferritin levelConclusions Iron deficiency is common in patients with chronic HF, relates to disease severity, and is a strong and independent predictor of outcome. In this study, ID appears to have greater predictive power than anemia. (Am Heart J 2013;165:575-582.e3.)</p
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