Diazirines are among the smallest photoreactive groups that form a reactive carbene upon light irradiation. This feature has been widely utilized in photoaffinity labeling to study ligand-receptor, ligand-enzyme and protein-protein interactions, and in the isolation and identification of unknown proteins. This review summarizes recent advances in the use of diazirines in photoaffinity labeling. (C) 2011 Elsevier Ltd. All rights reserved.</p
Many different reagents and methodologies have been utilised for the modification of synthetic and b...
Photoaffinity labeling is frequently employed for the investigation of ligand-receptor interactions ...
Photoaffinity labeling is frequently employed for the investigation of ligand-receptor interactions ...
Diazirines are among the smallest photoreactive groups that form a reactive carbene upon light irrad...
Diazirines are among the smallest photoreactive groups that form a reactive carbene upon light irrad...
Diazirines are among the smallest photoreactive groups that form a reactive carbene upon light irrad...
Target identification is a high-priority, albeit challenging, aspect of drug discovery. Diazirine-ba...
Photoaffinity labeling is a quintessential technique in studying and analyzing the interaction betwe...
Photoaffinity labeling is a quintessential technique in studying and analyzing the interaction betwe...
The use of light-activated chemical probes to study biological interactions was first discovered in ...
Based on the recent development of molecular biology, the investigation of biofunctional machinery a...
Based on the recent development of molecular biology, the investigation of biofunctional machinery a...
The 1,3,5-trisubstituted aryl diazirine(2) has been synthesised as a photoaffinity probe and has bee...
Photoaffinity labels are powerful tools for dissecting ligand–protein interactions, and they have a ...
Photoaffinity labeling is frequently employed for the investigation of ligand-receptor interactions ...
Many different reagents and methodologies have been utilised for the modification of synthetic and b...
Photoaffinity labeling is frequently employed for the investigation of ligand-receptor interactions ...
Photoaffinity labeling is frequently employed for the investigation of ligand-receptor interactions ...
Diazirines are among the smallest photoreactive groups that form a reactive carbene upon light irrad...
Diazirines are among the smallest photoreactive groups that form a reactive carbene upon light irrad...
Diazirines are among the smallest photoreactive groups that form a reactive carbene upon light irrad...
Target identification is a high-priority, albeit challenging, aspect of drug discovery. Diazirine-ba...
Photoaffinity labeling is a quintessential technique in studying and analyzing the interaction betwe...
Photoaffinity labeling is a quintessential technique in studying and analyzing the interaction betwe...
The use of light-activated chemical probes to study biological interactions was first discovered in ...
Based on the recent development of molecular biology, the investigation of biofunctional machinery a...
Based on the recent development of molecular biology, the investigation of biofunctional machinery a...
The 1,3,5-trisubstituted aryl diazirine(2) has been synthesised as a photoaffinity probe and has bee...
Photoaffinity labels are powerful tools for dissecting ligand–protein interactions, and they have a ...
Photoaffinity labeling is frequently employed for the investigation of ligand-receptor interactions ...
Many different reagents and methodologies have been utilised for the modification of synthetic and b...
Photoaffinity labeling is frequently employed for the investigation of ligand-receptor interactions ...
Photoaffinity labeling is frequently employed for the investigation of ligand-receptor interactions ...
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