Cochlear Hydrops Analysis Masking Procedure Results in Patients With Unilateral Meniere's Disease

Objective: To investigate the usefulness of the cochlear hydrops analysis masking procedure (CHAMP) as an additional diagnostic test in patients with definite unilateral Meniere's disease.Study Design: Prospective validation study for a diagnostic test.Setting: Tertiary referral center.Patients: Subjects (n = 22) with definite unilateral Meniere's disease.Interventions: The CHAMP test was performed in both ears of the patients.Main Outcome Measure: Difference in latency delay between the affected and the unaffected ears.Results: In 20 subjects, latency delays could be measured in both ears. The mean latency delay for the affected ears (0.55 ms; standard error, 0.12 ms) differs significantly from that for the unaffected ears (3.36 ms; standard error, 0.43 ms). With the standard criterion to separate ears with an abnormally short delay (Conclusion: Abnormal latency delays for CHAMP are delays shorter than 2 ms. Earlier results with CHAMP should be reconsidered using this criterion, instead of 0.3 ms.