Recombinant Gelatin Microspheres:Novel Formulations for Tissue Repair?
- Tuin, Annemarie
- Kluijtmans, Sebastiaan G.
- Bouwstra, Jan B.
- Harmsen, Martin C.
- Van Luyn, Marja J. A.
DOIAbstract
Microspheres (MSs) can function as multifunctional scaffolds in different approaches of tissue repair (TR), as a filler, a slow-release depot for growth factors, or a delivery vehicle for cells. Natural cell adhesion-supporting extracellular matrix components like gelatin are good materials for these purposes. Recombinant production of gelatin allows for on-demand design of gelatins, which is why we aim at developing recombinant gelatin (RG) MSs for TR. Two types of MSs (50</p
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