Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation. Physiol Rev 89: 147-191,2009; doi: 10.1152/physrev.00010.2008. - The incidence of the metabolic syndrome has taken epidemic proportions in the past decades, contributing to an increased risk of cardiovascular disease and diabetes. The metabolic syndrome can be defined as a cluster of cardiovascular disease risk factors including visceral obesity, insulin resistance, dyslipidemia, increased blood pressure, and hypercoagulability. The farnesoid X receptor (FXR) belongs to the superfamily of ligand-activated nuclear receptor transcription factors. FXR is activated by bile acids, and FXR-deficient (FXR-/-) mice display elevated...
OBJECTIVE-Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through dif...
Bile acids (BAs), the end products of cholesterol catabolism, are essential for the absorption of li...
International audienceOBJECTIVE Bile acids (BA) participate in the maintenance of metabolic homeosta...
Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of Bile Acids and Bile Acid Receptors in Met...
Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of Bile Acids and Bile Acid Receptors in Met...
Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of Bile Acids and Bile Acid Receptors in Met...
Objectives: Activation of the bile acid (BA) receptors farnesoid X receptor (FXR) or G protein-coupl...
Bile acid has been well known to serve as a hormone in regulating transcriptional activity of Farnes...
Over the past decade, it has become apparent that bile acids are involved in a host of activities be...
Over the past decade, it has become apparent that bile acids are involved in a host of activities be...
OBJECTIVE-Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through dif...
OBJECTIVE-Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through dif...
OBJECTIVE-Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through dif...
Over the past decade, it has become apparent that bile acids are involved in a host of activities be...
Bile acids act not only as natural detergents to facilitate fat absorption but also as signaling mol...
OBJECTIVE-Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through dif...
Bile acids (BAs), the end products of cholesterol catabolism, are essential for the absorption of li...
International audienceOBJECTIVE Bile acids (BA) participate in the maintenance of metabolic homeosta...
Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of Bile Acids and Bile Acid Receptors in Met...
Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of Bile Acids and Bile Acid Receptors in Met...
Lefebvre P, Cariou B, Lien F, Kuipers F, Staels B. Role of Bile Acids and Bile Acid Receptors in Met...
Objectives: Activation of the bile acid (BA) receptors farnesoid X receptor (FXR) or G protein-coupl...
Bile acid has been well known to serve as a hormone in regulating transcriptional activity of Farnes...
Over the past decade, it has become apparent that bile acids are involved in a host of activities be...
Over the past decade, it has become apparent that bile acids are involved in a host of activities be...
OBJECTIVE-Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through dif...
OBJECTIVE-Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through dif...
OBJECTIVE-Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through dif...
Over the past decade, it has become apparent that bile acids are involved in a host of activities be...
Bile acids act not only as natural detergents to facilitate fat absorption but also as signaling mol...
OBJECTIVE-Bile acids (BA) participate in the maintenance of metabolic homeostasis acting through dif...
Bile acids (BAs), the end products of cholesterol catabolism, are essential for the absorption of li...
International audienceOBJECTIVE Bile acids (BA) participate in the maintenance of metabolic homeosta...