In this study pulmonary vaccination with a new influenza subunit vaccine powder was evaluated. Vaccine powder was produced by spray-freeze drying (SFD) using the oligosaccharide inulin as stabilizer. Immune responses after pulmonary vaccination of BALB/c mice with vaccine powder were determined and compared to those induced by intramuscular and pulmonary vaccination with a conventional liquid subunit vaccine. All vaccinations were performed without adjuvant. Pulmonary vaccination with liquid subunit vaccine resulted in systemic Immoral (IgG) immune responses similar to intramuscular immunization. In contrast, the vaccine powder delivered by the pulmonary route, induced not only systemic Immoral (IgG) responses, but also cell-mediated (II-4,...
Background: Pulmonary immunization has recently gained increased interest as a means to induce both ...
Pulmonary immunization has gained increased recognition as a means of triggering both a mucosal and ...
The aim of this study was to investigate two different processes to produce a stable influenza subun...
In this study pulmonary vaccination with a new influenza subunit vaccine powder was evaluated. Vacci...
In this study pulmonary vaccination with a new influenza subunit vaccine powder was evaluated. Vacci...
Stabilization and ease of administration are two ways to substantially improve the use of current va...
Stabilization and ease of administration are two ways to substantially improve the use of current va...
Stabilization and ease of administration are two ways to substantially improve the use of current va...
Stabilization and ease of administration are two ways to substantially improve the use of current va...
One of the advantages of dry influenza vaccines over conventional liquid influenza vaccines is that ...
One of the advantages of dry influenza vaccines over conventional liquid influenza vaccines is that ...
One of the advantages of dry influenza vaccines over conventional liquid influenza vaccines is that ...
Prophylaxis against influenza could be improved by the development of a stable, easy to deliver, pot...
Prophylaxis against influenza could be improved by the development of a stable, easy to deliver, pot...
Prophylaxis against influenza could be improved by the development of a stable, easy to deliver, pot...
Background: Pulmonary immunization has recently gained increased interest as a means to induce both ...
Pulmonary immunization has gained increased recognition as a means of triggering both a mucosal and ...
The aim of this study was to investigate two different processes to produce a stable influenza subun...
In this study pulmonary vaccination with a new influenza subunit vaccine powder was evaluated. Vacci...
In this study pulmonary vaccination with a new influenza subunit vaccine powder was evaluated. Vacci...
Stabilization and ease of administration are two ways to substantially improve the use of current va...
Stabilization and ease of administration are two ways to substantially improve the use of current va...
Stabilization and ease of administration are two ways to substantially improve the use of current va...
Stabilization and ease of administration are two ways to substantially improve the use of current va...
One of the advantages of dry influenza vaccines over conventional liquid influenza vaccines is that ...
One of the advantages of dry influenza vaccines over conventional liquid influenza vaccines is that ...
One of the advantages of dry influenza vaccines over conventional liquid influenza vaccines is that ...
Prophylaxis against influenza could be improved by the development of a stable, easy to deliver, pot...
Prophylaxis against influenza could be improved by the development of a stable, easy to deliver, pot...
Prophylaxis against influenza could be improved by the development of a stable, easy to deliver, pot...
Background: Pulmonary immunization has recently gained increased interest as a means to induce both ...
Pulmonary immunization has gained increased recognition as a means of triggering both a mucosal and ...
The aim of this study was to investigate two different processes to produce a stable influenza subun...