High-dose chemotherapy as adjuvant treatment for high-risk breast cancer has been and is being investigated in a series of randomized trials. The preliminary information from 5 studies is difficult to interpret. The data are consistent with a modest benefit of high-dose therapy, but strong evidence for this is lacking. Additional follow-up and the results of several large trials outside the United States are awaited. Hitherto unrecognized pharmacologic interactions between high-dose agents and long-term to toxicities sub as cognitive function impairment complicate the issue considerably.</p
The aim of this retrospective study was to assess toxicity and efficacy of adjuvant high-dose chemot...
Purpose Adjuvant high-dose chemotherapy (HDC) with autologous hematopoietic stem-cell transplantatio...
The aim of this retrospective study was to assess toxicity and efficacy of adjuvant high-dose chemot...
High-dose chemotherapy as adjuvant treatment for high-risk breast cancer has been and is being inves...
The role of high-dose chemotherapy in the management of women with breast cancer remains one of the ...
In animal models of breast cancer and other malignancies, dose of chemotherapy correlates with curat...
Background. Uncontrolled studies suggest that high-dose chemotherapy is beneficial in patients with ...
Nowhere has there been more controversy in recent years than in the use of high dose chemotherapy (H...
Patients with high-risk breast cancer may benefit from dose-escalated chemotherapy. We studied toxic...
Patients with high-risk breast cancer may benefit from dose-escalated chemotherapy. We studied toxic...
Drug resistance is a major problem in the treatment of solid tumours. Based on a steep dose-response...
BACKGROUND: The use of high-dose adjuvant chemotherapy for high-risk primary breast cancer is contro...
BACKGROUND: The use of high-dose adjuvant chemotherapy for high-risk primary breast cancer is contro...
The aim of this retrospective study was to assess toxicity and efficacy of adjuvant high-dose chemot...
The aim of this retrospective study was to assess toxicity and efficacy of adjuvant high-dose chemot...
Purpose Adjuvant high-dose chemotherapy (HDC) with autologous hematopoietic stem-cell transplantatio...
The aim of this retrospective study was to assess toxicity and efficacy of adjuvant high-dose chemot...
High-dose chemotherapy as adjuvant treatment for high-risk breast cancer has been and is being inves...
The role of high-dose chemotherapy in the management of women with breast cancer remains one of the ...
In animal models of breast cancer and other malignancies, dose of chemotherapy correlates with curat...
Background. Uncontrolled studies suggest that high-dose chemotherapy is beneficial in patients with ...
Nowhere has there been more controversy in recent years than in the use of high dose chemotherapy (H...
Patients with high-risk breast cancer may benefit from dose-escalated chemotherapy. We studied toxic...
Patients with high-risk breast cancer may benefit from dose-escalated chemotherapy. We studied toxic...
Drug resistance is a major problem in the treatment of solid tumours. Based on a steep dose-response...
BACKGROUND: The use of high-dose adjuvant chemotherapy for high-risk primary breast cancer is contro...
BACKGROUND: The use of high-dose adjuvant chemotherapy for high-risk primary breast cancer is contro...
The aim of this retrospective study was to assess toxicity and efficacy of adjuvant high-dose chemot...
The aim of this retrospective study was to assess toxicity and efficacy of adjuvant high-dose chemot...
Purpose Adjuvant high-dose chemotherapy (HDC) with autologous hematopoietic stem-cell transplantatio...
The aim of this retrospective study was to assess toxicity and efficacy of adjuvant high-dose chemot...