In chronic allografts, graft vessels eventually develop so-called "transplant vascular sclerosis" or "intimal hyperplasia". A major question is whether the cells in the neointima are donor or recipient derived. The process of transplant vascular sclerosis closely resembles the remodeling of the vascular wall as seen when synthetic biodegradable small caliber vascular grafts are implanted. In this model, the cells in the newly developing neointima as well as neomedia are, by definition, recipient derived.By using cardiac allografts as well as aortic allografts exchanged between a female donor and a male recipient (rats), the origin of the neointimal vascular smooth muscle cells could be traced by looking for the Y-chromosome in isolated (alp...
Objective: Transplant vasculopathy consists of neointima formation in graft vasculature resulting fr...
To date, chronic transplant dysfunction (CTD) is recognized as the major cause of transplant loss lo...
Vascular disease is the main cause of disability and mortality in the western world and the major li...
In chronic allografts, graft vessels eventually develop so-called "transplant vascular sclerosis" or...
The development of transplant arteriosclerosis (TA) is today's most important problem in clinical or...
Background: Coronary artery disease is today's most important post-heart transplantation problem aft...
To date, clinical solid-organ transplantation has not achieved its goals as a long-term treatment fo...
Transplant arteriosclerosis (TA) is a major complication after solid organ transplantation. TA is ch...
To date, chronic transplant dysfunction (CTD) is recognized as the major cause of long-term transpla...
AbstractChronic rejection (CR) is the most common cause of late graft failure after solid organ tran...
Although advances in graft procurement, preservation, matching and immunosuppression have all contri...
Background. Chronic transplant dysfunction is the leading cause of long-term renal allograft loss. O...
Objective: Transplant vasculopathy consists of neointima formation in graft vasculature resulting fr...
To date, chronic transplant dysfunction (CTD) is recognized as the major cause of transplant loss lo...
Vascular disease is the main cause of disability and mortality in the western world and the major li...
In chronic allografts, graft vessels eventually develop so-called "transplant vascular sclerosis" or...
The development of transplant arteriosclerosis (TA) is today's most important problem in clinical or...
Background: Coronary artery disease is today's most important post-heart transplantation problem aft...
To date, clinical solid-organ transplantation has not achieved its goals as a long-term treatment fo...
Transplant arteriosclerosis (TA) is a major complication after solid organ transplantation. TA is ch...
To date, chronic transplant dysfunction (CTD) is recognized as the major cause of long-term transpla...
AbstractChronic rejection (CR) is the most common cause of late graft failure after solid organ tran...
Although advances in graft procurement, preservation, matching and immunosuppression have all contri...
Background. Chronic transplant dysfunction is the leading cause of long-term renal allograft loss. O...
Objective: Transplant vasculopathy consists of neointima formation in graft vasculature resulting fr...
To date, chronic transplant dysfunction (CTD) is recognized as the major cause of transplant loss lo...
Vascular disease is the main cause of disability and mortality in the western world and the major li...