Assembly of Lamb protein into the outer membrane of Escherichia coli

Assembly of outer membrane proteins is a very complicated process. It involves protein synthesis in the cytoplasm, transport of the newly synthesized protein across the cytoplasmic membrane and the periplasmic space, folding of the polypeptide chain into its proper conformation and - in some cases – conversion of the folded molecules into larger complexes, for example oli-gomers. In this thesis, several aspects of the synthesis and assembly of LamB protein, an outer membrane protein of Escherichia coli, are described. ... Zie: Summar