Protein tyrosine nitration (PTN) is a post-translational modification of proteins associated with a number of inflammatory diseases. While PTN is rather selective (not all proteins are modified and within a protein, only certain tyrosines are subject to nitration), no consensus sequence has been identified. Since PTN is a low-abundance post-translational modification, it is necessary to enrich modified proteins and/or to detect them with high selectivity and sensitivity. Until now this has been mostly accomplished with anti-nitrotyrosine antibodies in combination with two-dimensional gel electrophoresis and mass spectrometry. We propose a chemical labeling approach designed to allow enrichment of tyrosine-nitrated peptides independent of th...
A new proteomics technique for analyzing 3-nitrotyrosine-containing peptides is presented here. This...
Tyrosine nitration is the consequence of a complex machinery of formation and merging of oxygen and ...
The overproduction of reactive oxygen and nitrogen species (ROS and RNS) can have deleterious effect...
Protein tyrosine nitration (PTN) is a post-translational modification of proteins associated with a ...
Protein tyrosine nitration (PTN) is a posttranslational modification resulting from oxidative/nitros...
Elevated levels of protein tyrosine nitration have been found in various neurodegenerative diseases ...
Nitrotyrosine is a post-translationally modified amino acid with distinctly different properties tha...
Protein tyrosine nitration (PTN) is a post-translational modification occurring under the action of ...
Protein tyrosine nitration (PTN) is a post-translational modification occurring under the action of ...
Protein tyrosine nitration (PTN) is a post-translational modification occurring under the action of ...
Nitration of tyrosine residues in proteins has been mainly characterised by immunoanalytical methods...
Protein tyrosine nitration by oxidative and nitrate stress is important in the pathogenesis of many ...
Nitration of tyrosine residues has been shown to be an important oxidativemodification in proteins a...
The nitration of protein tyrosine residues represents an important posttranslational modification du...
A new proteomics technique for analyzing 3-nitrotyrosine-containing peptides is presented here. This...
Tyrosine nitration is the consequence of a complex machinery of formation and merging of oxygen and ...
The overproduction of reactive oxygen and nitrogen species (ROS and RNS) can have deleterious effect...
Protein tyrosine nitration (PTN) is a post-translational modification of proteins associated with a ...
Protein tyrosine nitration (PTN) is a posttranslational modification resulting from oxidative/nitros...
Elevated levels of protein tyrosine nitration have been found in various neurodegenerative diseases ...
Nitrotyrosine is a post-translationally modified amino acid with distinctly different properties tha...
Protein tyrosine nitration (PTN) is a post-translational modification occurring under the action of ...
Protein tyrosine nitration (PTN) is a post-translational modification occurring under the action of ...
Protein tyrosine nitration (PTN) is a post-translational modification occurring under the action of ...
Nitration of tyrosine residues in proteins has been mainly characterised by immunoanalytical methods...
Protein tyrosine nitration by oxidative and nitrate stress is important in the pathogenesis of many ...
Nitration of tyrosine residues has been shown to be an important oxidativemodification in proteins a...
The nitration of protein tyrosine residues represents an important posttranslational modification du...
A new proteomics technique for analyzing 3-nitrotyrosine-containing peptides is presented here. This...
Tyrosine nitration is the consequence of a complex machinery of formation and merging of oxygen and ...
The overproduction of reactive oxygen and nitrogen species (ROS and RNS) can have deleterious effect...