The Multilevel Approach to Repeated Measures for Complete and Incomplete Data

Repeated measurements often are analyzed by multivariate analysis of variance (MANOVA). An alternative approach is provided by multilevel analysis, also called the hierarchical linear model (HLM), which makes use of random coefficient models. This paper is a tutorial which indicates that the HLM can be specified in many different ways, corresponding to different sets of assumptions about the covariance matrix of the repeated measurements. The possible assumptions range from the very restrictive compound symmetry model to the unrestricted multivariate model. Thus, the HLM can be used to steer a useful middle road between the two traditional methods for analyzing repeated measurements. Another important advantage of the multilevel approach to analyzing repeated measures is the fact that it can be easily used also if the data are incomplete. Thus it provides a way to achieve a fully multivariate analysis of repeated measures with incomplete data.