Shotgun sequencing enables the reconstruction of genomes from complex microbial communities, but because assembly does not reconstruct entire genomes, it is necessary to bin genome fragments. Here we present CONCOCT, a new algorithm that combines sequence composition and coverage across multiple samples, to automatically cluster contigs into genomes. We demonstrate high recall and precision on artificial as well as real human gut metagenome data sets
Metagenomic sequencing and assembly have become important approaches for the in situ characterisatio...
Metagenomic sequencing and assembly have become important approaches for the in situ characterisatio...
Most current approaches for analyzing metagenomic data rely on comparisons to reference genomes, but...
Shotgun sequencing enables the reconstruction of genomes from complex microbial communities, but bec...
Shotgun sequencing enables the reconstruction of genomes from complex microbial communities, but bec...
Shotgun sequencing enables the reconstruction of genomes from complex microbial communities, but bec...
[[abstract]]Metagenomics, the application of shotgun sequencing, facilitates the reconstruction of t...
[[abstract]]Metagenomics, the application of shotgun sequencing, facilitates the reconstruction of t...
Sequencing technologies allow the sequencing of microbial communities directly from the environment ...
Sequencing technologies allow the sequencing of microbial communities directly from the environment ...
Assembly of metagenomic sequence data into microbial genomes is of fundamental value to improving ou...
Grouping large fragments assembled from shotgun metagenomic sequences to deconvolute complex microbi...
Abstract Background Due to the complexity of microbial communities, de novo assembly on next generat...
Grouping large genomic fragments assembled from shotgun metagenomic sequences to deconvolute complex...
Grouping large genomic fragments assembled from shotgun metagenomic sequences to deconvolute complex...
Metagenomic sequencing and assembly have become important approaches for the in situ characterisatio...
Metagenomic sequencing and assembly have become important approaches for the in situ characterisatio...
Most current approaches for analyzing metagenomic data rely on comparisons to reference genomes, but...
Shotgun sequencing enables the reconstruction of genomes from complex microbial communities, but bec...
Shotgun sequencing enables the reconstruction of genomes from complex microbial communities, but bec...
Shotgun sequencing enables the reconstruction of genomes from complex microbial communities, but bec...
[[abstract]]Metagenomics, the application of shotgun sequencing, facilitates the reconstruction of t...
[[abstract]]Metagenomics, the application of shotgun sequencing, facilitates the reconstruction of t...
Sequencing technologies allow the sequencing of microbial communities directly from the environment ...
Sequencing technologies allow the sequencing of microbial communities directly from the environment ...
Assembly of metagenomic sequence data into microbial genomes is of fundamental value to improving ou...
Grouping large fragments assembled from shotgun metagenomic sequences to deconvolute complex microbi...
Abstract Background Due to the complexity of microbial communities, de novo assembly on next generat...
Grouping large genomic fragments assembled from shotgun metagenomic sequences to deconvolute complex...
Grouping large genomic fragments assembled from shotgun metagenomic sequences to deconvolute complex...
Metagenomic sequencing and assembly have become important approaches for the in situ characterisatio...
Metagenomic sequencing and assembly have become important approaches for the in situ characterisatio...
Most current approaches for analyzing metagenomic data rely on comparisons to reference genomes, but...