Theranostic in early detection of recurring prostate cancer: 64CuCl2
- Gianluca Valentini
- Paola Panichelli
- Gioia Pigotti
- Beatrice Giacobbi
- Domenico Martini
- Giulio Milanese
- Paolo Mengoni
DOIAbstract
Aim: To evaluate the use of PET/CT with 64CuCl2 in recurring prostate cancer after surgery in patients with low PSA level (<2). Introduction: Previous works* demonstrated as 64CuCl2 is a PET probe in prostate cancer in mice with xenografts of prostate cancer.Moreover, it was described** in seven patients the role of 64CuCl2 PET/CT in staging of prostate cancer. Method: 32 Patients with low PSA level (<2) in recurring prostate post-surgical cancer were studied with 64CuCl2 PET/CT executed at 1, 3 and 24 h after injection of 200–400 MBq (medium activity 4 MBq/kg). A dosimetric analysis was done with manual VOI on various organs (Liver, Kidneys, Spleen, lumbar spine L4-L5 and Prostate as target). Coregistered imaging with CT to calculate...
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