Evaluating the Relationship between Diabetes and Cancer in a Cohort

Background/aim: Epidemiological studies indicate that the risk of several types of cancer is high in diabeticpatients. The aim of this study is to evaluate the association between diabetes and diabetes related cancers in a cohortdesign. Materials and methods: The baseline survey was conducted as a community screening programme from2007 to 2009 in a population over 30 years of age. Diabetes definition was based on fasting blood glucose level ≥ 126mg/dl and self-reported diabetes history. Data on incident cancer cases and pathological types were obtained from theİzmir Cancer Registry between 2007-2013. Odds ratios (OR) were estimated for the relationship between diabetesand diabetes-related cancer types for men and women separately and adjusted for BMI and age. Odds Ratio and 95%confidence intervals were calculated using logistic regression models in IBM SPSS Statistics 24.0. Results: Datafrom 10,375 women (65.4%) and 5,494 men (34.6%) who did not declare any cancer in 2007 were evaluated. Thecumulative incidence of diabetes related cancers was 2,293 per 100,000 in men and 1,455 per 100,000 in women. Totaldiabetes related cancer incidence was higher in diabetics (3,770 per 100,000) than nondiabetics (2,109 per 100,000)in men. Conclusion: There was no statistically significant association between diabetes and cancers. The analyses canbe repeated in the future when the cohort gets older and more incident cases of cancers occur.