Increased mean platelet volume in children with sepsis as a predictor of mortality

Our aim is to investigate the correlation between the mean platelet volume (MPV) levels and platelet counts of the septic children with 28-day mortality risk. MPV at admission (MPVadm), MPV at 72nd hour (MPV72h) and the difference between these two parameters (Delta MPV72h-adm) and platelet counts were recorded retrospectively. The control group consisted of 100 healthy children matched for age, gender, and ethnicity. One hundred eighty six children were enrolled into the study. The study group had significant higher MPV values than those of control group. There were 156 survivors and 32 nonsurvivors in study group with a mortality rate of 17%. Nonsurvivors had significantly higher MPVadm (p: 0.001), MPV72h (p: 0.001), Delta MPV72h-adm (p