Febrile neutropenic episodes in children with lymphoma and malignant solid tumors

Objective: To analyze febrile neutropenic episodes (FNEs) of children with lymphoma and malignant solid tumors (MSTs). Methods: Medical records of children with cancer who had FNEs between July 01, 2005-August 01, 2007 were analyzed. Neutropenia was defined as an absolute neutrophil count (ANC) of 10days in 14% of FNEs. Shock developed in 5 FNEs. Conclusion: Twenty-two percent of FNEs were treated with monotherapy, and in 42% of episodes, parenteral antibiotics were used for less than one week. The majority of patients were hospitalized for less then 10 days. Neither fever control time, nor antibiotic modification rate was different in the cephalosporin and carbapenem groups