Mesangial C4d deposition is independently associated with poor renal survival in patients with primary focal segmental glomerulosclerosis

Background C4d deposition is defined as the footprint of immune injury and it is associated with unfavorable renal outcomes in patients with IgA nephropathy. We searched whether mesangial C4d deposition is associated with poor renal survival in patients with primary focal segmental glomerulosclerosis (FSGS)