Investigating the risk factors for antibiotic lock therapy failure in pediatric cancer: a single center retrospective analysis

Background. Catheter-related bloodstream infection (CRBSI) is one of the most common complications of central lines. Data concerning the effectiveness and safety of antibiotic lock therapy (ALT), especially in pediatric hematology and oncology patients, have not yet reached sufficient levels of evidence. We aimed to share our center's experience on ALT in pediatric cancer and to investigate the causes of ALT failure